Regulating cell shape during cytokinesis
Regulating cell shape during cytokinesis
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DOI：
10.1007/11664550_11
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发表时间：
2006-01-01
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影响因子：
--
通讯作者：
Robinson, DN
中科院分区：
文献类型：
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作者：
Effler, JC;Iglesias, PA;Robinson, DN
在胞质分裂的最后一步，细胞必须重新排列它们的形状，以产生两个大小相等的子细胞。为此，必须协调各种蛋白质的时空分布。在本文中，我们回顾了这个过程中的一些基本步骤。此外，我们认为，在这个过程中的一个关键步骤是马达蛋白的反馈调节。在这样做的过程中，我们表明，细胞形状变化的研究可以受益于系统级的方法。
During cytokinesis, the last step in cell division, cells must rearrange their shape so as to produce two daughter cells of equal size. To this end, the temporal and spatial distribution of a wide variety of proteins must be coordinated. In this paper we review some of the basic steps in the process. Moreover, we argue that a key step in the process is the feedback regulation of motor proteins. In doing so, we show that the study of cellular shape change can benefit from a systems-level approach.