Does Helicobacter pylori infection play a role in lung cancer?
Does Helicobacter pylori infection play a role in lung cancer?
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DOI：
10.1016/j.rmed.2005.02.038
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发表时间：
2005-10-01
影响因子：
4.3
通讯作者：
Aksoy, F
中科院分区：
文献类型：
--
作者：
Ece, F;Hatabay, NF;Aksoy, F
背景：幽门螺杆菌感染是一种世界性的常见病，可导致许多胃肠道和呼吸道疾病。有人认为，这些呼吸系统疾病之一是肺癌。方法：选取43例非小细胞肺癌患者和28例对照组进行研究。采用免疫印迹法检测幽门螺杆菌IgG （RIDA Blot Helicobacter）。所有受试者均检测VacA和CagA基因的存在。结果：肿瘤患者血清中抗幽门螺杆菌IgG阳性分别为40例（93%）和12例（42%），明显高于对照组(P
Background: Helicobacter pylori infection is a world-wide common disease and leads to many gastrointestinal and respiratory illnesses. It is suggested that one of these respiratory illnesses is lung cancer.Methods: Forty-three patients with non-small cell Lung cancer and 28 control subjects have been included to this study. H. pylori status of the patients and controls was determined by immunoblot for the detection of IgG (RIDA Blot Helicobacter). All subjects were examined to evaluate the presence of VacA and CagA gene.Results: Seropositivity of anti H. pylori IgG was significantly higher in cancer patients than in control groups, 40 (93%) and 12 (42%), respectively (P