GDB: the Human Genome Database
GDB: the Human Genome Database
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DOI：
10.1093/nar/26.1.94
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发表时间：
1998-01-01
影响因子：
14.9
通讯作者：
Li, PWD
中科院分区：
文献类型：
--
作者：
Letovsky, SI;Cottingham, RW;Li, PWD
基因组数据库（GDB，http://www.gdb.org）是关于人类基因、克隆、STS、多态性和图谱的数据的公共储存库，GDB条目彼此高度交联，与文献引用和其他数据库中的条目高度交联，包括序列数据库、OMIM和小鼠基因组数据库。来自大型基因组中心的图谱数据和较小的图谱工作持续地添加到GDB中。可以通过多种方法搜索数据库，从关键词搜索到复杂查询，去年的主要功能扩展包括正在进行的综合人类基因组图谱的计算，称为综合图谱，以及使用这些图谱支持位置查询和图形显示，GDB图谱查看器（Mapview）的功能已经扩展到包括图谱打印和特定查询结果的图形显示，HUGO命名委员会继续与GDB合作策划拟议的和官方的基因符号和相关数据，随着基因组研究的重点从作图转向测序和功能分析，GDB模式的范围正在扩大，我们正在添加基因功能和表达的表示，并改善我们对人类多态性和突变的描述。
The Genome Database (GDB, http://www.gdb.org) is a public repository of data on human genes, clones, STSs, polymorphisms and maps, GDB entries are highly cross-linked to each other, to literature citations and to entries in other databases, including the sequence databases, OMIM, and the Mouse Genome Database, Mapping data from large genome centers and smaller mapping efforts are added to GDB on an ongoing basis, The database can be searched by a variety of methods, ranging from keyword searches to complex queries, Major functionality extensions in the last year include the ongoing computation of integrated human genome maps, called Comprehensive Maps, and the use of those maps to support positional queries and graphic displays, The capabilities of the GDB map viewer (Mapview) have been extended to include map printing and the graphical display of ad hoc query results, The HUGO Nomenclature Committee continues to curate the proposed and official gene symbols and related data in collaboration with GDB, As genome research shifts its emphasis from mapping to sequencing and functional analysis, the scope of the GDB schema is being extended, We are in the process of adding representations of gene function and expression, and improving our representation of human polymorphism and mutation.