Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity.
Targeting of heparanase-modified syndecan-1 by prosecretory mitogen lacritin requires conserved core GAGAL plus heparan and chondroitin sulfate as a novel hybrid binding site that enhances selectivity.
复制标题
原分泌促分裂原乳泌素靶向乙酰肝素酶修饰的 Syndecan-1 需要保守的核心 GAGAL 加上乙酰肝素和硫酸软骨素作为新的混合结合位点,以增强选择性。
DOI:
10.1074/jbc.m112.422717
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发表时间:
2013
期刊:
影响因子:
--
通讯作者:
Laurie,GordonW
中科院分区:
文献类型:
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作者:
Zhang,Yinghui;Wang,Ningning;Raab,RonaldW;McKown,RobertL;Irwin,JacobA;Kwon,Inchan;vanKuppevelt,ToinH;Laurie,GordonW