Protein disulfide isomerases - a way to tackle malaria.
Protein disulfide isomerases - a way to tackle malaria.
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DOI:
10.1016/j.pt.2023.05.007
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发表时间:
2023-06
影响因子:
9.6
通讯作者:
F. Angrisano;Amelia Ford;A. Blagborough;H. Bullen
中科院分区:
文献类型:
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作者:
F. Angrisano;Amelia Ford;A. Blagborough;H. Bullen
Protein disulfide isomerases (PDIs) ensure that specific substrate proteins are correctly folded. PDI activity plays an essential role in malaria transmission. Here we provide an overview of the role of PDIs in malaria-causingPlasmodiumparasites and outline why PDI inhibition could be a novel way to treat malaria and prevent transmission.