The hidden history of the snowshoe hare, Lepus americanus: extensive mitochondrial DNA introgression inferred from multilocus genetic variation
The hidden history of the snowshoe hare, Lepus americanus: extensive mitochondrial DNA introgression inferred from multilocus genetic variation
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DOI：
10.1111/mec.12886
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发表时间：
2014-09-01
影响因子：
4.9
通讯作者：
Alves, Paulo C.
中科院分区：
文献类型：
--
作者：
Melo-Ferreira, Jose;Seixas, Fernando A.;Alves, Paulo C.
杂交驱动着许多物种或当地种群的进化轨迹，评估种间基因流的地理范围和遗传影响可能为理解种群分化或混合物的适应性相关性提供宝贵的线索。在北美，野兔（兔属（Lepus spp.）是生态系统动态的关键物种，它们的进化历史可能受到杂交的影响。在这里，我们重建了北美三种分布最广的野兔的物种形成历史--雪鞋兔（Lepus americanus）、白尾长耳野兔（L. townsendii）和黑尾长耳野兔L. californicus）-通过分析八个核标记和一个线粒体DNA（mtDNA）位点（6240 bp; 94个标本）的序列变异。基于多位点-多种聚结的系统发育表明L. americanus在2.7Ma时发生了类似的分叉，L. californicus和L. townsendii的分裂时间较晚（与1.2Ma相似）。在L。americanus，推测其存在着一个与2.0 Ma相似的深潜分化历史，这与北美其他物种的主要物种形成事件相吻合。虽然隔离迁移模型表明，核基因流通常是罕见的或不存在的物种或主要遗传群体，合并模拟的mtDNA分歧揭示了历史mtDNA渐渗从L。californicus进入太平洋西北部的L.美国人这一发现标志着这些物种之间过去的网状关系的历史，这可能影响了基因组的其他部分，并影响了野兔在气候变化期间的适应潜力。
Hybridization drives the evolutionary trajectory of many species or local populations, and assessing the geographic extent and genetic impact of interspecific gene flow may provide invaluable clues to understand population divergence or the adaptive relevance of admixture. In North America, hares (Lepus spp.) are key species for ecosystem dynamics and their evolutionary history may have been affected by hybridization. Here we reconstructed the speciation history of the three most widespread hares in North America - the snowshoe hare (Lepus americanus), the white-tailed jackrabbit (L. townsendii) and the black-tailed jackrabbit (L. californicus) - by analysing sequence variation at eight nuclear markers and one mitochondrial DNA (mtDNA) locus (6240 bp; 94 specimens). A multilocus-multispecies coalescent-based phylogeny suggests that L. americanus diverged similar to 2.7 Ma and that L. californicus and L. townsendii split more recently (similar to 1.2 Ma). Within L. americanus, a deep history of cryptic divergence (similar to 2.0 Ma) was inferred, which coincides with major speciation events in other North American species. While the isolation-with-migration model suggested that nuclear gene flow was generally rare or absent among species or major genetic groups, coalescent simulations of mtDNA divergence revealed historical mtDNA introgression from L. californicus into the Pacific Northwest populations of L. americanus. This finding marks a history of past reticulation between these species, which may have affected other parts of the genome and influence the adaptive potential of hares during climate change.