Everyday People Sing a Simple Song: Establishing a Core Outcome for Life Participation.
Everyday People Sing a Simple Song: Establishing a Core Outcome for Life Participation.
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日常生活中人们唱着一首简单的歌：建立生活参与的核心成果。
DOI：
10.1097/tp.0000000000002477
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发表时间：
2019
期刊：
影响因子：
6.2
通讯作者：
Brennan,DanielC
中科院分区：
文献类型：
--
作者：
Aala,Amtul;Brennan,DanielC
几项移植研究报告了以患者为中心的结果，以帮助改善长期肾移植受者护理，并希望将这些结果标准化用于所有未来的研究。[1]这些建议大多是短期的，往往不一致，而且不完整。在临床试验中报告这些结果缺乏统一性，这阻碍了共同决策。医生，护理人员和患者对报告的内容感兴趣，以指导治疗和制定临床指南。认识到这一需求，最近制定了几项共识指南，包括2016年临床数据交换标准联盟和2016年肾脏移植标准化结局。肾脏移植标准化结局（SONG-Tx）结局是一项全球倡议，旨在为肾移植试验制定核心结局集。2，3于2015年启动，这是一个3阶段的过程;第一阶段是对各种临床研究的系统性综述，第二阶段是使用德尔菲调查与国际多利益相关者小组（患者、护理人员、临床医生、研究人员、政策制定者、行业成员），制定了基于共识的优先成果领域清单;随后是第三阶段，利用协商一致研讨会审查和最后确定这些核心成果集。总体排名前10位的结果是导致移植物损失的肾排斥、肾功能、对其他器官的损害、癌症（所有）、糖尿病、皮肤癌、心血管疾病、感染、体重增加和食欲过旺，并且前5位的心理社会或身体症状是对家庭的影响、抑郁、对工作的影响、胃肠道疾病、糖尿病、糖尿病。
Several studies in transplantation have reported patient centered outcomes to help improve long-term kidney transplant recipient care, with the hope of standardizing these outcomes for all future studies. 1 These are mostly found to be short term, often inconsistent, and incomplete. There is lack of uniformity in reporting these outcomes in clinical trials, which hinders shared decision making. Physicians, caregivers, and patients have an interest in what is reported to guide treatment and develop clinic guidelines. Acknowledging this need, several consensus guidelines have been developed recently, including Clinical Data Interchange Standards Consortium 2016 and Standardized Outcomes in Nephrology—Transplantation 2016.Standardized Outcomes in Nephrology-Transplantation (SONG-Tx) Outcomes is a global initiative to develop a core outcome set for trials in kidney transplantation. 2, 3 Initiated in 2015, this was a 3-phase process; first phase was a systematic review of various clinical studies, second phase was to use a Delphi survey with an international multistakeholder panel (patients, caregivers, clinicians, researchers, policy makers, members from industry) which developed a consensus-based prioritized list of outcome domains; followed by the third phase, using a consensus workshop to review and finalize these core outcome sets. The top 10 ranked outcomes overall were kidney rejection leading to graft loss, kidney function, damage to other organs, cancer (all), diabetes, skin cancer, cardiovascular disease, infection, weight gain, and excessive appetite, and the top 5 psychosocial or physical symptoms were impact on family, depression, impact on work, gastrointestinal