Sleep disorders and atopic dermatitis: A 2-way street?
Sleep disorders and atopic dermatitis: A 2-way street?
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DOI：
10.1016/j.jaci.2018.08.005
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发表时间：
2018-10-01
影响因子：
14.2
通讯作者：
Chiang, Bor-Luen
中科院分区：
文献类型：
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作者：
Chang, Yung-Sen;Chiang, Bor-Luen
睡眠障碍在特应性皮炎（AD）患者中非常常见，是导致生活质量受损的主要因素。睡眠障碍通常被视为AD的症状之一，也是疾病严重程度的衡量标准之一。在这篇综述中，我们描述了与AD相关的各种睡眠障碍以及睡眠障碍对AD患者的广泛影响。我们还讨论了我们目前对AD患者睡眠障碍机制的理解。睡眠障碍与AD的关系可能是双向的，并可能形成恶性循环。因此，我们建议将睡眠障碍视为AD的合并症，定期筛查和双向管理策略是必要的，同样注重维持疾病控制和实施改善睡眠的特定策略。
Sleep disturbance is very common in patients with atopic dermatitis (AD) and is a major factor leading to impaired quality of life. Sleep disturbance is often viewed as one of the symptoms of AD and one of the measures of disease severity. In this review we describe a variety of sleep disorders associated with AD and a wide range of effect that sleep disorders have on patients with AD. We also discuss our current understanding of the mechanism of sleep disturbance in patients with AD. The relationship between sleep disorders and AD might be bidirectional and could form a vicious cycle. Therefore we suggest viewing sleep disorders as a comorbidity of AD for which regular screening and bidirectional management strategies are indicated, with equal focus on maintaining disease control and implementing specific strategies to improve sleep.