Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers
Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers
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DOI：
10.1016/s0003-9969(99)00025-4
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发表时间：
1999-06-01
影响因子：
3
通讯作者：
Giardina, R
中科院分区：
文献类型：
--
作者：
Zappacosta, B;Persichilli, S;Giardina, R
谷胱甘肽，尿酸和总抗氧化活性的浓度，表示为Trolox（一种水溶性维生素E类似物）当量，在健康的非吸烟者和吸烟者的唾液中测量之前和之后吸一支烟。吸烟者和非吸烟者的尿酸浓度和总自由基捕获抗氧化能力没有统计学显著差异，但吸烟者的谷胱甘肽浓度显著（p < 0.05）更高。吸一根香烟引起谷胱甘肽浓度显著降低（p < 0.05）。唾液抗氧化能力可能影响个体对烟草应激的敏感性。(C)1999 Elsevier Science Ltd.保留所有权利。
Concentrations of glutathione, uric acid and total antioxidant activity, expressed as Trolox (a water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-smokers and smokers before and just after smoking a single cigarette. There was no statistically significant difference between smokers and non-smokers in uric acid concentrations and total radical-trapping antioxidant capacity, but glutathione concentrations were significantly (p < 0.05) higher in smokers. Smoking of a single cigarette induced a significant reduction in glutathione concentration (p < 0.05). Salivary antioxidant power may affect individual sensitivity toward tobacco stress. (C) 1999 Elsevier Science Ltd. All rights reserved.