Digestion, excretion, and energy value of fructooligosaccharides in healthy humans
Digestion, excretion, and energy value of fructooligosaccharides in healthy humans
复制标题
DOI：
10.1093/ajcn/64.3.324
复制
发表时间：
1996-09-01
影响因子：
7.1
通讯作者：
Galmiche, JP
中科院分区：
文献类型：
--
作者：
Molis, C;Flourie, B;Galmiche, JP
在6名健康志愿者中，对低聚果糖（FOS）在人体胃肠道中的命运进行了为期11天的评价。经过一个平衡阶段后，20.1 g FOS/d分三次相同的餐后剂量给药。通过单餐后肠道抽吸法测定FOS及其组成成分的远端回肠排出量，并测定粪便和尿液中FOS的排泄量。大多数摄入的FOS，89 +/- 8.3%（（c）在条+/- SEM上），在小肠中没有被吸收，并且没有通过粪便排出，表明到达结肠的部分完全被结肠植物群发酵。一小部分摄入的FOS在尿液中回收，FOS的平均估计能量值为9.5kJ/g。我们的结论是，在健康的人中，FOS仅在小肠中轻微消化，然后在结肠中发酵，导致能量产生减少。
The fate of fructooligosaccharides (FOS) in the human gastrointestinal tract was evaluated in six healthy volunteers over an 11-d period. After an equilibration phase, 20.1 g FOS/d was given in three identical postprandial doses. Distal ileal output of FOS and their constituent components were determined by intestinal aspiration after a single meal, and the amounts of FOS excreted in stools and urine were also measured. Most of ingested FOS, 89 +/- 8.3% ((c) over bar +/- SEM), was not absorbed in the small intestine, and none was excreted in stools, indicating that the portion reaching the colon was completely fermented by colonic flora. A small fraction of ingested FOS was recovered in urine, The mean estimated energy value of FOS was 9.5 kJ/g. We conclude that in healthy humans, FOS are only slightly digested in the small intestine and then fermented in the colon, resulting in reduced energy production.