The PHQ-9 - Validity of a brief depression severity measure
The PHQ-9 - Validity of a brief depression severity measure
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DOI：
10.1046/j.1525-1497.2001.016009606.x
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发表时间：
2001-09-01
影响因子：
5.7
通讯作者：
Williams, JBW
中科院分区：
文献类型：
--
作者：
Kroenke, K;Spitzer, RL;Williams, JBW
目的：虽然相当多的注意力集中在改善抑郁症的检测，严重程度的评估在指导治疗决策中也很重要。因此，我们研究了一个简短的，新的措施抑郁症severity.MEASUREMENTS的有效性：患者健康问卷（PHQ）是一个自我管理的版本的PRIME-MD诊断工具常见的精神障碍。PHQ-9是抑郁模块，它将9个DSM-IV标准中的每一个评分为“0”（根本没有）到“3”（几乎每天）。8个初级保健诊所和7个妇产科诊所的6 000名病人完成了PHQ-9。使用20项简式一般健康调查，自我报告的病假和诊所访问的结构效度进行评估。与困难有关的。标准效度进行了评估，对一个独立的结构化的心理健康专业人士（MHP）采访的样本中的580 patients.RESULTS：作为PHQ-9抑郁症的严重程度增加，有一个大幅度下降的功能状态的所有6 SF-20分量表。此外，与医疗有关的困难、病假和医疗保健利用率也有所增加。以MHP再访作为判断标准，PHQ-9评分≥ 10分诊断重性抑郁症的敏感性为88%，特异性为88%。PHQ-9评分为5分。十，十五。轻度、中度、中重度、重度抑郁症各20例。结果在初级保健和妇产科样本中相似。除了对抑郁症进行基于标准的诊断外，PHQ-9也是抑郁症严重程度的可靠和有效的衡量标准。这些特点加上它的简洁性使PHQ-9成为一个有用的临床和研究工具。
OBJECTIVE: While considerable attention has focused on improving the detection of depression, assessment of severity Is also important in guiding treatment decisions. Therefore, we examined the validity of a brief, new measure of depression severity.MEASUREMENTS: The Patient Health Questionnaire (PHQ) is a self-administered version of the PRIME-MD diagnostic instrument for common mental disorders. The PHQ-9 is the depression module, which scores each of the 9 DSM-IV criteria as "0" (not at all) to "3" (nearly every day). The PHQ-9 was completed by 6,000 patients in 8 primary care clinics and 7 obstetrics-gynecology clinics. Construct validity was assessed using the 20-item Short-Form General Health Survey, self-reported sick days and clinic visits. and symptom-related difficulty. Criterion validity was assessed against an Independent structured mental health professional (MHP) interview in a sample of 580 patients.RESULTS: As PHQ-9 depression severity Increased, there was a substantial decrease in functional status on all 6 SF-20 subscales. Also, symptom-related difficulty, sick days, and health care utilization increased. Using the MHP reinterview as the criterion standard, a PHQ-9 score greater than or equal to 10 had a sensitivity of 88% and a specificity of 88% for major depression. PHQ-9 scores of 5. 10, 15. and 20 represented mild, moderate, moderately severe, and severe depression, respectively. Results were similar in the primary care and obstetrics-gynecology samples.CONCLUSION. In addition to making criteria-based diagnoses of depressive disorders, the PHQ-9 Is also a reliable and valid measure of depression severity. These characteristics plus Its brevity make the PHQ-9 a useful clinical and research tool.