Reversible DNA micro-patterning using the fluorous effect.
Reversible DNA micro-patterning using the fluorous effect.
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DOI:
10.1039/c7cc00288b
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发表时间:
2017-03-09
期刊:
影响因子:
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通讯作者:
Clark AW
中科院分区:
文献类型:
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作者:
Flynn GE;Withers JM;Macias G;Sperling JR;Henry SL;Cooper JM;Burley GA;Clark AW
We described the use of the fluorous effect as a simple and reversible immobilisation technique for DNA. We describe a new method for the immobilisation of DNA into defined patterns with sub-micron resolution, using the fluorous effect. The method is fully reversible via a simple solvent wash, allowing the patterning, regeneration and re-patterning of surfaces with no degradation in binding efficiency following multiple removal/attachment cycles of different DNA sequences.