Effect of carbohydrate-protein supplementation on endurance training adaptations.

Effect of carbohydrate-protein supplementation on endurance training adaptations.
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DOI:
10.1007/s00421-020-04450-1
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发表时间:
2020-10
影响因子:
3
通讯作者:
Betts JA
Betts JA
中科院分区:
医学3区
文献类型:
--
作者:
Alghannam AF;Templeman I;Thomas JE;Jedrzejewski D;Griffiths S;Lemon J;Byers T;Reeves S;Gonzalez JT;Thompson D;Bilzon J;Tsintzas K;Betts JA

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研究运动后蛋白质喂养对耐力运动训练适应性反应的影响。在随机平行组设计中,25 名健康男性和女性每周在跑步机上以 70-75% 最大摄氧量 (VO2max) 跑步 30-60 分钟 4 次,完成了为期 6 周的耐力运动训练。参与者立即和运动后 1 小时摄入每公斤体重 (g kg BM−1) 1.6 g 碳水化合物 (CHO) 或等热量碳水化合物-蛋白质溶液 (CHO-P;0.8 g 碳水化合物 kg BM−1 + 0.8 g 蛋白质 kg BM−1)。在基线和随访时采集过期气体、血液和肌肉活检样本。运动训练均改善了两组的最大摄氧量 (p ≤ 0.001),但无论是绝对值还是相对于体重的增量(分别为 0.2 ± 0.2 L min−1 和 3.0± 2 mL kg−1 min−1),组间增量均无差异。使用 CHO-P(4.18 ± 0.18 至 4.23 ± 0.17 g dL−1)或 CHO(4.17 ± 0.17 至 4.12 ± 0.22 g dL−1)时,血浆白蛋白浓度没有发生变化;相互作用: p > 0.05)。运动训练后,相对于 CHO (+ 4%),CHO-P 中雷帕霉素 (mTOR) 机械靶点基因表达上调 (+ 46%;p = 0.025)。在 6 周的耐力运动训练中,运动后补充蛋白质可上调骨骼肌中 mTOR 的表达。然而,各组之间最大摄氧量的改善幅度相似。
To examine the influence of post-exercise protein feeding upon the adaptive response to endurance exercise training. In a randomised parallel group design, 25 healthy men and women completed 6 weeks of endurance exercise training by running on a treadmill for 30–60 min at 70–75% maximal oxygen uptake (VO2max) 4 times/week. Participants ingested 1.6 g per kilogram of body mass (g kg BM−1) of carbohydrate (CHO) or an isocaloric carbohydrate–protein solution (CHO-P; 0.8 g carbohydrate kg BM−1 + 0.8 g protein kg BM−1) immediately and 1 h post-exercise. Expired gas, blood and muscle biopsy samples were taken at baseline and follow-up. Exercise training improved VO2max in both groups (p ≤ 0.001), but this increment was not different between groups either in absolute terms or relative to body mass (0.2 ± 0.2 L min−1 and 3.0 ± 2 mL kg−1 min−1, respectively). No change occurred in plasma albumin concentration from baseline to follow-up with CHO-P (4.18 ± 0.18 to 4.23 ± 0.17 g dL−1) or CHO (4.17 ± 0.17 to 4.12 ± 0.22 g dL−1; interaction: p > 0.05). Mechanistic target of rapamycin (mTOR) gene expression was up-regulated in CHO-P (+ 46%; p = 0.025) relative to CHO (+ 4%) following exercise training. Post-exercise protein supplementation up-regulated the expression of mTOR in skeletal muscle over 6 weeks of endurance exercise training. However, the magnitude of improvement in VO2max was similar between groups.
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