Cut Points for Clinical Muscle Weakness Among Older Americans
Cut Points for Clinical Muscle Weakness Among Older Americans
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DOI：
10.1016/j.amepre.2016.12.022
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发表时间：
2017-07-01
影响因子：
5.5
通讯作者：
Clarke, Philippa J.
中科院分区：
文献类型：
--
作者：
Duchowny, Kate A.;Peterson, Mark D.;Clarke, Philippa J.
简介：肌无力是残疾、慢性病和早期死亡的重要指标。握力是一种简单、经济有效的整体肌肉力量测量方法。美国国立卫生研究院基金会最近提出了临床肌无力的性别特异性握力切入点。然而，这些标准是使用非全国代表性的数据制定的。这项研究使用了 65 岁以上美国人的全国代表性数据，以确定临床肌肉无力的种族和性别特异性切点，并按性别量化老年黑人和白人中的患病率。方法：使用分类和回归树模型，根据 7,688 名个体（57% 女性；8% 黑人；平均年龄，74.6 [SD = 6.79] 年）来自 2016 年 1 月至 4 月期间的 2010/2012 年健康与退休研究。然后使用确定的切点来量化按种族/性别亚组划分的虚弱患病率。结果：55% 的男性（最大握力 < 39 公斤）和 47% 的女性（最大握力 < 22 公斤）被归类为虚弱。黑人男性（最大握力 < 40 公斤）和女性（最大握力 < 31 公斤）的切点较高，而且与白人相比，无力的发生率（分别为 57% 和 88%）更高。 55% 的人步态速度较慢（< 0.8 m/秒）。结论：虚弱的患病率大大高于之前的报告，强调了使用人群数据来识别最有不良健康结果风险的个人的重要性。这是第一项在全国代表性样本中按种族和性别确定肌无力切点的研究。 (C) 2017 年美国预防医学杂志。由爱思唯尔公司出版。保留所有权利。
Introduction: Muscle weakness is an important indicator of disability, chronic disease, and early mortality. Grip strength is a simple, cost-effective measure of overall muscle strength. The Foundation of the National Institutes of Health recently proposed sex-specific grip strength cut points for clinical muscle weakness. However, these criteria were established using non - nationally representative data. This study used nationally representative data on Americans aged >= 65 years to identify race-and sex-specific cut points for clinical muscle weakness and quantify prevalence among older blacks and whites by sex.Methods: Classification and Regression Tree models were used to identify cut points based on individual-level grip strength associated with slow gait speed (< 0.8 m/second) among 7,688 individuals (57% female; 8% black; mean age, 74.6 [SD = 6.79] years) from the 2010/2012 Health and Retirement Study during January - April 2016. Identified cut points were then used to quantify the prevalence of weakness by race/sex subgroup.Results: Fifty-five percent of men (maximum grip strength < 39 kg) and 47% of women (maximum grip strength < 22 kg) were classified as weak. Higher cut points were identified for black men (maximum grip strength < 40 kg) and women (maximum grip strength < 31 kg), and the prevalence of weakness (57% and 88%, respectively) was higher compared with whites. Fifty-five percent of individuals had slow gait speed (< 0.8 m/second).Conclusions: Prevalence of weakness was substantially higher than previous reports, underscoring the importance of using population-level data to identify individuals at greatest risk for adverse health outcomes. This is the first study to establish cut points for muscle weakness in a nationally representative sample by race and sex. (C) 2017 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.