FDG-PET/CT for Detection of Extramedullary Disease in 2 Pediatric Patients With AML.
FDG-PET/CT for Detection of Extramedullary Disease in 2 Pediatric Patients With AML.
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FDG-PET/CT 用于检测 2 例 AML 儿科患者的髓外疾病。
DOI：
10.1097/mph.0000000000000447
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发表时间：
2016
期刊：
影响因子：
--
通讯作者：
Matsushita T.
中科院分区：
文献类型：
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作者：
Matsui M;Yamanaka J;Shichino H;Sato N;Kubota K;Matsushita T.
正电子发射断层扫描与计算机断层扫描 (PET/CT) 相结合是一种很有前途的诊断方法，用于检测急性髓系白血病髓外疾病 (EMD)。我们研究了 2 名患有急性髓系白血病的儿童，他们在诊断时和缓解时接受了 PET 评估 EMD。我们通过 PET 在 2 例病例中检测到 5 个 EMD 病灶，其中只有 2 个在临床检查中可检测到。我们的病例表明，在评估和监测这种疾病的程度方面，PET 比单独体检的敏感性更高。
Positron emission tomography combined with computed tomography (PET/CT) is a promising diagnostic procedure for the detection of extramedullary disease (EMD) in acute myeloid leukemia. We studied 2 children with acute myeloid leukemia who underwent PET to assess for EMD at diagnosis as well as in remission. We detected 5 EMD lesions in 2 cases with PET, only 2 of which were detectable on clinical examination. Our cases show PET’s increased sensitivity over physical examination alone in assessing and monitoring the extent of this disease.