Silver-Catalyzed Reduction of Quinolines in Water
Silver-Catalyzed Reduction of Quinolines in Water
复制标题
银催化还原水中的喹啉
DOI：
10.1021/acs.orglett.9b01055
复制
发表时间：
2019-05-17
期刊：
影响因子：
5.2
通讯作者：
Bi, Xihe
中科院分区：
文献类型：
--
作者：
Wang, Yan;Dong, Baobiao;Bi, Xihe
本文报道了一种无碱无配体的银催化还原喹啉和缺电子芳香族氮杂芳烃的反应。机理研究表明，有效还原物种为Ag-H。这种多功能的催化协议提供了方便，环境友好，和实用的获得各种1，2，3，4-四氢喹啉衍生物在室温下。
A ligand- and base-free silver-catalyzed reduction of quinolines and electron-deficient aromatic N-heteroarenes in water has been described. Mechanistic studies revealed that the effective reducing species was Ag-H. This versatile catalytic protocol provided facile, environmentally friendly, and practical access to a variety of 1,2,3,4-tetrahydroquinoline derivatives at room temperature.