Bacterial penetration in the apical pocket wall of advanced human periodontitis.
Bacterial penetration in the apical pocket wall of advanced human periodontitis.
复制标题
晚期人类牙周炎根尖袋壁中的细菌渗透。
DOI：
10.1111/j.1600-0765.1980.tb00315.x
复制
发表时间：
1980
影响因子：
3.5
通讯作者：
R. Frank
中科院分区：
文献类型：
--
作者：
R. Frank
在研究的14例晚期人类慢性牙周炎患者中，有8例观察到牙周袋尖壁存在细菌。在全身麻醉下切除根尖结缔组织和结缔组织。在增大的上皮细胞间隙中可见以革兰氏阴性细胞壁为主的丝状、棒状和球状微生物。在结缔组织中，这些微生物存在于严重受损的细胞碎片和胶原原纤维中。在龈下牙菌斑的顶端和袋壁的连接上皮之间，可见数层多形核白细胞，并有大量吞噬体显示被吞噬的细菌。在慢性牙周炎的最后阶段，细菌侵入袋尖壁是可能的。
The presence of bacteria in the apical wall of periodontal pockets has been observed in 8 cases of advanced human chronic periodontitis out of a total of 14 patients studied. The apical junctional epithelium and the underlying connective tissue were removed under general anesthesia. Filaments, rodshaped and coccoid microorganisms with predominant Gram-negative cell walls were observed in the enlarged epithelial intercellular spaces. In the connective tissue, these microorganisms were found among badly damaged cellular fragments and collagen fibrils. Between the apical sub-gingival plaque and the junctional epithelium of the pocket wall, several layers of polymorphonuclear leukocytes were observed with numerous phagosomes showing engulfed bacteria. Bacterial invasion of the apical wall of the pockets is possible in the final stages of human chronic periodontitis.