CONNECTION, A MICROCOMPUTER PROGRAM FOR STORING AND ANALYZING STRUCTURAL-PROPERTIES OF NEURAL CIRCUITS
CONNECTION, A MICROCOMPUTER PROGRAM FOR STORING AND ANALYZING STRUCTURAL-PROPERTIES OF NEURAL CIRCUITS
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DOI：
10.1016/0010-4809(90)90007-y
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发表时间：
1990-02-01
期刊：
影响因子：
--
通讯作者：
VANDEBILT, MT
中科院分区：
文献类型：
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作者：
NICOLELIS, MAL;TINONE, G;VANDEBILT, MT
本文介绍了一种基于微机的系统（连接系统）的应用，该系统旨在处理研究人员通常分析的神经解剖信息，并参与神经回路结构特性的研究。该系统首先可以作为一个易于访问的数据库，包含来自中枢神经系统核的生理和解剖数据，这些数据定义了一个具有多达45个元素及其细分和连接的网络。一旦建立了来自特定网络的数据库并将其存储在文件中，该系统的例程就可以用于根据其传入和传出对核进行分类，并且还可以显示连接任何一对核及其各自长度（突触数量）的所有可能的通路。这样一个系统作为一个辅助工具，在神经解剖学和电生理学研究的作用进行了讨论，提出了从分析的结果，参与caridovascular功能控制在高等脊椎动物的神经回路。
The application of a microcomputer-based system (the Connection system) designed to deal with neuroanatomical information commonly analyzed by researchers and involved in the study of structural properties of neural circuits is presented. This system can be employed at first as a readily-accessible database containing physiological and anatomical data from nuclei of the central nervous system which define a network with up to 45 elements and their subdivisions and connections. Once the database from a specific network is built and stored in a file, routines of this system can be used to classify the nuclei in terms of their afferents and efferents and also to display all possible pathways linking any pair of nuclei and their respective length (number of synapses). The role of such a system as an auxiliary tool in neuroanatomical and electrophysiological research is discussed by presenting the results obtained from the analysis of the neural circuits involved in caridovascular function control in higher vertebrates.