Assessing hydration status: the elusive gold standard
Assessing hydration status: the elusive gold standard
复制标题
DOI：
10.1080/07315724.2007.10719661
复制
发表时间：
2007-10-01
影响因子：
3.5
通讯作者：
Armstrong, Lawrence E.
中科院分区：
文献类型：
--
作者：
Armstrong, Lawrence E.
认识到全身水分 (TBW) 周转情况很复杂，并且没有一种测量方法适用于所有情况，本综述评估了 13 种水合作用评估技术。尽管针对 TBW 和细胞外体积存在经过验证的实验室方法，但没有证据无可辩驳地证明任何浓度测量（包括血浆渗透压 (P-osm)）能够准确代表日常活动期间 TBW 的增加和损失。此外，一份血液或尿液样本不能有效代表波动的 TBW 和液体室。未来的研究应该（a）评估实时评估水合作用的新技术，这些技术是精确、准确、可靠、非侵入性、便携、廉价、安全和简单的； (b) 阐明各种情况下 P-osm 和 TBW 振荡之间的关系。
Acknowledging that total body water (TBW) turnover is complex, and that no measurement is valid for all situations, this review evaluates 13 hydration assessment techniques. Although validated laboratory methods exist for TBW and extracellular volume, no evidence incontrovertibly demonstrates that any concentration measurement, including plasma osmolality (P-osm), accurately represents TBW gain and loss during daily activities. Further, one blood or urine sample cannot validly represent fluctuating TBW and fluid compartments. Future research should (a) evaluate novel techniques that assess hydration in real time and are precise, accurate, reliable, non-invasive, portable, inexpensive, safe, and simple; and (b) clarify the relationship between P-osm and TBW oscillations in various scenarios.