Detection of patent foramen ovale by Doppler color flow mapping in patients undergoing cardiac catheterization.
Detection of patent foramen ovale by Doppler color flow mapping in patients undergoing cardiac catheterization.
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通过多普勒彩色血流图检测接受心导管插入术的患者的卵圆孔未闭。
DOI：
10.1016/0002-9149(91)90727-3
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发表时间：
1991
期刊：
影响因子：
--
通讯作者：
Taylor,AL
中科院分区：
文献类型：
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作者：
Brickner,ME;Grayburn,PA;Fadel,B;Carry,MM;Eichhorn,EJ;Lange,RA;Taylor,AL
尸检研究表明，在20%到35%的普通人群中，卵圆孔是开放的。1，2尽管它通常被认为是偶然发现，但最近的临床研究表明，卵圆孔未闭(PFO)可能是矛盾的栓塞的重要途径。3，4此外，在右心压升高或右室顺应性降低的情况下，由于跨PFO的右向左分流而引起的低氧血症可能发生。5，6尽管超声造影已被用于确定可疑的PFO患者的右向左分流，4、7-10这项技术可能受限于它对从右向左的血流成分的依赖，以及识别这种血流的少数心动周期。多谱勒彩色血流图可以成像房间隔缺损两个方向上的血流，11也提供了识别跨PFO的血流的可能性。因此，我们测试了这样的假设，即彩色血流图可以准确地检测到通过PFO的流动产生的小喷流。
Autopsy studies have demonstrated that the foramen ovale is patent in 20 to 35% of the general population.1,2Although it is generally considered to be an incidental finding, recent clinical studies suggest that the patent foramen ovale (PFO) may serve as an important route for paradoxical embolization.3,4In addition, hypoxemia due to right-to-left shunting across a PFO may occur in the setting of elevated right heart pressures or decreased right ventricular compliance.5,6Although contrast echocardiography has been used to identify right-to-left shunting in patients with a suspected PFO,4,7–10this technique may be limited by its dependence on a right-to-left component of flow and by the small number of cardiac cycles in which to identify such flow. Doppler color flow mapping, which can image flow jets in either direction across an atrial septal defect,11also offers the potential to identify flow across a PFO. Thus, we tested the hypothesis that color flow mapping could accurately detect small jets resulting from flow across a PFO.