THE INCIDENCE OF AIR-FLOW OBSTRUCTION IN BRONCHIAL-CARCINOMA, ITS RELATION TO BREATHLESSNESS, AND RESPONSE TO BRONCHODILATOR THERAPY
THE INCIDENCE OF AIR-FLOW OBSTRUCTION IN BRONCHIAL-CARCINOMA, ITS RELATION TO BREATHLESSNESS, AND RESPONSE TO BRONCHODILATOR THERAPY
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DOI：
10.1016/0954-6111(95)90090-x
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发表时间：
1995-04-01
影响因子：
4.3
通讯作者：
MUERS, MF
中科院分区：
文献类型：
--
作者：
CONGLETON, J;MUERS, MF
呼吸困难是原发性支气管癌患者的常见症状，并且通常无法得到很好的控制。大多数患者曾经或现在吸烟，因此患有慢性阻塞性肺病 (COPD) 的风险很高。前瞻性研究了支气管癌患者气流阻塞的发生率、其与呼吸困难的关系以及对支气管扩张剂治疗的反应。我们对过去 12 个月内到我们门诊就诊的连续 57 名诊断为支气管癌的患者进行了研究（22 名女性，35 名男性，平均年龄 68.4 岁）。进行肺活量测定并评估呼吸困难。气流受阻者 (FEV(1):FVC
Breathlessness is a common symptom in patients with primary bronchial carcinoma and is often not well-controlled. Most patients are ex- or current smokers, and therefore are at high risk for co-existing chronic obstructive pulmonary disease (COPD). The incidence of airflow obstruction in patients with bronchial carcinoma, its relation to breathlessness, and response to bronchodilator therapy was examined prospectively. Fifty-seven consecutive patients attending our outpatient clinic with bronchial carcinoma diagnosed in the preceding 12 months were studied (22 female, 35 male, mean age 68 . 4 years). Spirometry was performed and breathlessness rated. Those with airflow obstruction (FEV(1):FVC