High efficiency multishot interleaved spiral-in/out: acquisition for high-resolution BOLD fMRI.
High efficiency multishot interleaved spiral-in/out: acquisition for high-resolution BOLD fMRI.
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DOI：
10.1002/mrm.24476
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发表时间：
2013-08
影响因子：
3.3
通讯作者：
Buracas, Giedrius T.
中科院分区：
文献类型：
--
作者：
Jung, Youngkyoo;Samsonov, Alexey A.;Liu, Thomas T.;Buracas, Giedrius T.
Growing demand for high spatial resolution BOLD functional MRI faces a challenge of the spatial resolution vs. coverage or temporal resolution tradeoff, which can be addressed by methods that afford increased acquisition efficiency. Spiral acquisition trajectories have been shown to be superior to currently prevalent echo-planar imaging in terms of acquisition efficiency, and high spatial resolution can be achieved by employing multiple-shot spiral acquisition. The interleaved spiral in-out trajectory is preferred over spiral-in due to increased BOLD signal CNR and higher acquisition efficiency than that of spiral-out or non-interleaved spiral in/out trajectories, but to date applicability of the multi-shot interleaved spiral in-out for high spatial resolution imaging has not been studied. Herein we propose multi-shot interleaved spiral in-out acquisition and investigate its applicability for high spatial resolution BOLD fMRI. Images reconstructed from interleaved spiral-in and -out trajectories possess artifacts caused by differences in T2* decay, off-resonance and k-space errors associated with the two trajectories. We analyze the associated errors and demonstrate that application of conjugate phase reconstruction and spectral filtering can substantially mitigate these image artifacts. After applying these processing steps, the multishot interleaved spiral in-out pulse sequence yields high BOLD CNR images at in-plane resolution below 1x1 mm while preserving acceptable temporal resolution (4 s) and brain coverage (15 slices of 2 mm thickness). Moreover, this method yields sufficient BOLD CNR at 1.5 mm isotropic resolution for detection of activation in hippocampus associated with cognitive tasks (Stern memory task). The multi-shot interleaved spiral in-out acquisition is a promising technique for high spatial resolution BOLD fMRI applications.
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影响因子：
3.3
作者：
Truong, Trong-Kha;Chen, Nan-kuei;Song, Allen W.
通讯作者：
Song, Allen W.
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NOLL, DC;MEYER, CH;MACOVSKI, A
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MACOVSKI, A
影响因子：
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MACOVSKI, A
影响因子：
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