Some determinants of intake of glucose+saccharin solutions

Some determinants of intake of glucose+saccharin solutions
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葡萄糖糖精溶液摄入量的一些决定因素

DOI:
10.1016/0031-9384(80)90192-4
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发表时间:
1980
影响因子:
2.9
通讯作者:
David F. Foster
David F. Foster
中科院分区:
医学3区
文献类型:
--
作者:
James C. Smith;David F. Foster

文献摘要

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在目前的三个实验中,进行了测试,以查看摄入后因素是否在由3%葡萄糖和0.125%糖精溶液的组合引起的过量饮酒中起作用。第一个实验表明,当向大鼠提供葡萄糖+糖精(G+S)溶液时,每日总热量摄入量显著增加,从食物中摄取的热量比例降低。尽管饮用G+S会导致饮食发生变化,但实验2比较了不同浓度的葡萄糖溶液和G+S溶液的饮用情况,证明大鼠饮用大量G+S溶液是为了味道,而不是卡路里。最后的实验比较了对各种浓度的糖精、葡萄糖或G+S溶液的偏好测试,并且显示跨G+S浓度的偏好数据在定性上与糖精偏好数据相似,并且与葡萄糖数据不同,即使操纵的是浓度中的葡萄糖的量。
In the present three experiments, tests were run to see if postingestional factors played a role in the excessive drinking elicited by the combination of 3% glucose and 0.125% saccharin solutions. The first experiment showed a marked increase in the total daily caloric intake and a decrease in the proportion of calories taken from the food when the glucose+saccharin (G+S) solution was presented to rats. In spite of this alteration of diet induced by G+S drinking, Experiment 2, which compared the drinking of various concentrations of glucose solutions and G+S solutions, demonstrated that the rat drinks these large quantities of the G+S solution for taste, not calories. The final experiment compared preference tests on various concentrations of saccharin, glucose or G+S solutions and showed that preference data across concentrations of G+S were qualitatively similar to the saccharin preference data, and different from the glucose data, even though it was the amount of glucose in the concentrations that was manipulated.