A Three-Compartment Chemically-Driven Molecular Information Ratchet
A Three-Compartment Chemically-Driven Molecular Information Ratchet
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DOI：
10.1021/ja302711z
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发表时间：
2012-05-23
影响因子：
15
通讯作者：
Wilson, Adam
中科院分区：
文献类型：
--
作者：
Carlone, Armando;Goldup, Stephen M.;Wilson, Adam
我们描述了一种三室轮烷信息棘轮，其中大环化合物可以沿着非手性（不考虑同位素标记）轨道在任一方向上定向运输。基于手性 DMAP 的催化剂促进苯甲酰化反应，从而加速大环的位移，将其主要输送到由催化剂的手性决定的特定端室。
We describe a three-compartment rotaxane information ratchet in which the macrocycle can be directionally transported in either direction along an achiral (disregarding isotopic labeling) track. Chiral DMAP-based catalysts promote a benzoylation reaction that ratchets the displacement of the macrocycle, transporting it predominantly to a particular end compartment determined by the handedness of the catalyst.