Influence of the number of lymph nodes examined on staging of gastric cancer
Influence of the number of lymph nodes examined on staging of gastric cancer
复制标题
DOI：
10.1046/j.0007-1323.2001.01875.x
复制
发表时间：
2001-10-01
影响因子：
9.6
通讯作者：
Kim, JP
中科院分区：
文献类型：
--
作者：
Lee, HK;Yang, HK;Kim, JP
背景：根据 1997 年国际抗癌联盟肿瘤淋巴结转移分类，胃癌淋巴结分期是基于转移淋巴结的数量。本研究的目的是评估检查的淋巴结数量是否影响胃癌的分期。方法：对1986年至1995年连续4789例接受根治性切除（RO）的胃癌患者进行回顾性研究。根据检查的淋巴结数量对患者进行分类。比较转移淋巴结数量和分期分层生存率。结果：15个及以上淋巴结患者与15个以下患者的转移淋巴结数量和IIIA期生存率存在显着差异。在仅限于具有 15 个或更多淋巴结的患者的分析中，除 IIIB 之外的任何阶段的分期分层生存率均不随淋巴结产量而显着变化，其中检查淋巴结少于 20 个的亚组与具有 35 个或更多淋巴结的患者之间存在显着差异。 结论：只要检查至少 15 个淋巴结，检查淋巴结的数量不会显着影响胃癌的淋巴结分期。 检查了。对于 IIIB 期，可能需要超过 15 个淋巴结才能达到最佳分期。
Background: Nodal staging for gastric cancer according to the 1997 Union Internacional Contra la Cancrum tumour node metastasis classification is based on the number of metastatic lymph nodes. The aim of this study was to evaluate whether the number of lymph nodes examined affected staging of gastric cancer.Methods: A retrospective study was performed in 4789 consecutive patients with gastric cancer, who had undergone curative resection (RO) from 1986 to 1995. Patients were classified according to the number of nodes examined. The number of metastatic lymph nodes and stage-stratified survival were compared.Results: There were significant differences in the number of metastatic lymph nodes and survival in stage IIIA between patients with 15 or more lymph nodes and those with fewer than 15 nodes. In analysis restricted to patients with 15 or more nodes, stage-stratified survival did not vary significantly with lymph node yields for any stage except IIIB, in which there was a significant difference between the subgroup with fewer than 20 examined lymph nodes and patients with 35 or more nodes.Conclusion: The number of lymph nodes examined did not significantly affect node staging of gastric cancer as long as at least 15 nodes were examined. For stage IIIB, more than 15 lymph nodes may be required for optimal staging.