Selective Recording of Urinary Bladder Fullness from the Extradural Sacral Roots.
Selective Recording of Urinary Bladder Fullness from the Extradural Sacral Roots.
复制标题
从硬膜外骶根选择性记录膀胱充盈度。
DOI：
10.1109/embc44109.2020.9176038
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Metcalfe B
中科院分区：
文献类型：
--
作者：
Metcalfe B
管理膀胱对于脊髓创伤后的临床医生和患者至关重要。控制膀胱的骶前根刺激器已作为临床技术使用多年，但这些设备无法测量膀胱的充盈度或检测反射性排尿的开始。为了解决这一根本限制，有必要开发一种记录编码膀胱充盈度的神经信号的方法。本文提出了一种使用多电极袖带记录来自硬膜外骶根的膀胱传入的概念验证技术。结果是在绵羊身上进行的急性体内实验提供的。
Managing the urinary bladder is of primary importance to clinicians and patients after trauma to the spinal cord. Sacral Anterior Root Stimulators that control the bladder have been available as clinical technology for many years, however these devices cannot measure the fullness of the urinary bladder or detect the onset of reflex voiding. In order to address this fundamental limitation, it is necessary to develop a method for recording the neural signals that encode bladder fullness. This paper presents a proof of concept technique for recording bladder afferents from the extradural sacral roots using a multiple electrode cuff. Results are provided from acute in-vivo experiments performed in sheep.