Impact of Cowpea-Based Food Containing Fish Meal Served With Vitamin C-Rich Drink on Iron Stores and Hemoglobin Concentrations in Ghanaian Schoolchildren in a Malaria Endemic Area
Impact of Cowpea-Based Food Containing Fish Meal Served With Vitamin C-Rich Drink on Iron Stores and Hemoglobin Concentrations in Ghanaian Schoolchildren in a Malaria Endemic Area
复制标题
DOI：
10.1177/0379572115596253
复制
发表时间：
2015-09-01
影响因子：
1.9
通讯作者：
Steiner-Asiedu, Matilda
中科院分区：
文献类型：
--
作者：
Egbi, Godfred;Ayi, Irene;Steiner-Asiedu, Matilda
背景：营养性贫血是加纳学龄儿童的一个公共卫生问题。有必要采用饮食调整策略来解决这个问题，通过学校和家庭喂养programmes.Objective：要评估的有效性，豇豆为基础的食物含有鱼粉与维生素C丰富的饮料，以提高铁存储和血红蛋白浓度在加纳schoolchild.Methods：这项研究涉及横截面基线和营养干预阶段。有150名6至12岁的参与者。他们被随机分为3组，鱼粉-维生素C（n = 50），维生素C（n = 50）和对照组（n = 50），并给予不同的豇豆为基础的饮食6个月的时间。根据标准程序测量身高和体重，通过24小时回忆和食物频率问卷获得饮食数据，通过Hemocue血红蛋白测定仪测定血红蛋白浓度，通过酶联免疫吸附测定法测定血清铁蛋白和补体反应蛋白（CRP）。参与者的血液样本进行了检查疟疾寄生虫血症和粪便蠕虫使用Giemsa染色和Kato-Katz techniques，respectively.Results：平均铁蛋白浓度组间无显着差异。鱼粉-维生素C组（128.4 ± 7.2/8.3 ± 10.6 g/L）和对照组（123.1 ± 6.6/4.2 ± 10.4 g/L）之间血红蛋白浓度的终点线平均值或变化不同，P <0.05。鱼粉维生素C组贫血患病率（19.5%）与维生素C组（9.3%）和对照组（12.2%）相比有显著性差异。在基线和终点线，研究参与者的疟疾寄生虫血症和高CRP水平分别为58%和80%，然后是55%和79%。结论：以含3%鱼粉的豇豆为基础的食物，配以富含维生素C的饮料，可提高血红蛋白浓度，降低贫血患病率。
Background: Nutritional anemia is a public health problem among Ghanaian schoolchildren. There is need to employ dietary modification strategies to solve this problem through school and household feeding programs.Objective: To evaluate the effectiveness of cowpea-based food containing fish meal served with vitamin C-rich drink to improve iron stores and hemoglobin concentrations in Ghanaian schoolchildren.Methods: The study involved cross-sectional baseline and nutrition intervention phases. There were 150 participants of age 6 to 12 years. They were randomly assigned to 3 groups, fish meal -vitamin C (n = 50), vitamin C (n = 50), and control (n = 50), and given different cowpea-based diets for a 6-month period. Height and weight measurements were done according to the standard procedures, dietary data were obtained by 24-hour recall and food frequency questionnaire, hemoglobin concentrations were determined by Hemocue Hemoglobinometer, and serum ferritin and complement-reactive protein (CRP) were determined by enzyme-linked immunosorbent assay. Participants' blood samples were examined for malaria parasitemia and stools for helminthes using Giemsa stain and Kato-Katz techniques, respectively.Results: Mean ferritin concentration was not significantly different among groups. End line mean or change in hemoglobin concentrations between fish meal-vitamin C group (128.4 7.2/8.3 +/- 10.6 g/L) and control (123.1 +/- 6.6/4.2 +/- 10.4 g/L) were different, P < .05. Change in prevalence of anemia in fish meal-vitamin C group (19.5%) was different compared to those of vitamin C group (9.3%) and the control (12.2%). Levels of malaria parasitemia and high CRP among study participants at baseline and end line were 58% and 80% then 55% and 79%, respectively. Level of hookworm infestation was 13%.Conclusion: Cowpea-based food containing 3% fish meal and served with vitamin C-rich drink improved hemoglobin concentration and minimized the prevalence of anemia among the study participants.