Prevalence and variability of current depressive disorder in 27 European countries: a population-based study.
Prevalence and variability of current depressive disorder in 27 European countries: a population-based study.
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DOI：
10.1016/s2468-2667(21)00047-5
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发表时间：
2021-10
期刊：
影响因子：
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通讯作者：
Alonso J
中科院分区：
文献类型：
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作者：
Arias-de la Torre J;Vilagut G;Ronaldson A;Serrano-Blanco A;Martín V;Peters M;Valderas JM;Dregan A;Alonso J
我们的目的是估计目前抑郁症的患病率在27个欧洲国家，并探讨欧洲国家之间的患病率和性别的差异。在这项基于人群的研究中，我们分析了来自27个欧洲国家的受访者的数据，这些受访者被纳入了2013年至2015年期间收集的第二波欧洲健康访谈调查。我们使用八项患者健康问卷（PHQ-8）评估当前抑郁症的患病率，抑郁症定义为PHQ-8评分为10分或更高。计算所有27个国家总体和每个国家单独的患病率估计值和95% CI。我们使用从负二项回归模型获得的粗患病率和调整后的患病率来评估患病率的变化（国家与欧洲其他国家）。我们对总样本进行了所有分析，并按性别分层。我们的分析样本包括258888人，其中117310人（加权比例47.8%）为男性，141578人（52.2%）为女性。当前抑郁障碍的总体患病率为6.38%（95%CI 6.24 - 6.52），各国之间存在重要差异，范围从捷克共和国的2.58%（2.14 - 3.02）到冰岛的10.33%（9.33 - 11.32）。女性的患病率（7.74%[7.53 - 7.95]）高于男性（4.89%[4.71 - 5.08]），除芬兰和克罗地亚外，所有国家都存在明显的性别差异。与我们样本中的其他欧洲国家相比，校正后患病率最高的国家是德国（1·80 [1·71-1·89]）和卢森堡（1·50 [1·35-1·66]），校正后患病率最低的国家是斯洛伐克（0·28 [0·24-0·33]）和捷克共和国（0·32 [0·27-0·38]）。抑郁症虽然在欧洲很常见，但各国之间的患病率差异很大。这些结果可以作为监测欧洲国家抑郁症患病率和规划卫生保健资源和服务的基线。英国医学研究理事会和CIBER流行病学和公共卫生（CIBERESP）。
We aimed to estimate the prevalence of current depressive disorder in 27 European countries, and to explore differences in prevalence between European countries and by gender. In this population-based study, we analysed data from respondents living in 27 European countries who were included in the second wave of the European Health Interview Survey, collected between 2013 and 2015. We assessed the prevalence of current depressive disorder using the eight-item Patient Health Questionnaire (PHQ-8), with depressive disorder defined as a PHQ-8 score of 10 or higher. Prevalence estimates and 95% CIs were calculated for all 27 countries overall and for each country individually. We assessed variation in prevalence (country vs the rest of Europe) using crude and adjusted prevalence ratios obtained from negative binomial regression models. We did all analyses for the total sample and stratified by gender. Our analysis sample comprised 258 888 individuals, of whom 117 310 (weighted proportion 47·8%) were men and 141 578 (52·2%) were women. The overall prevalence of current depressive disorder was 6·38% (95% CI 6·24–6·52) with important variation across countries, ranging from 2·58% (2·14–3·02) in the Czech Republic to 10·33% (9·33–11·32) in Iceland. Prevalence was higher in women (7·74% [7·53–7·95]) than in men (4·89% [4·71–5·08]), with clear gender differences for all countries except Finland and Croatia. Compared with the other European countries in our sample, those with the highest adjusted prevalence ratios were Germany (1·80 [1·71–1·89]) and Luxembourg (1·50 [1·35–1·66]), and those with the lowest adjusted prevalence ratios were Slovakia (0·28 [0·24–0·33]) and the Czech Republic (0·32 [0·27–0·38]). Depressive disorders, although common across Europe, vary substantially in prevalence between countries. These results could be a baseline for monitoring the prevalence of current depressive disorder both at a country level in Europe and for planning health-care resources and services. UK Medical Research Council and CIBER Epidemiology and Public Health (CIBERESP).