The influence of the dT.dG mispair on the activity of the human DNA(cytosine-5)methyltransferase.
The influence of the dT.dG mispair on the activity of the human DNA(cytosine-5)methyltransferase.
复制标题
dT.dG 错配对人类 DNA(胞嘧啶-5)甲基转移酶活性的影响。
DOI:
10.1016/0006-291x(87)90570-5
复制
发表时间:
1987
影响因子:
3.1
通讯作者:
Smith,SS
中科院分区:
文献类型:
--
作者:
Baker,DJ;Hardy,TA;Smith,SS
Synthetic oligodeoxynucleotides containing a dT·dG mispair at a centrally located d(pCG) dimer are methylated at a moderate rate by highly purified human DNA(cytosine-5)methyltransferase (E.C. 2.1.1.37). The presence of a mispaired dT in one strand induced the enzyme to preferentially methylate the opposite strand.