Behavioral genetics of thermosensation and hygrosensation in Drosophila
Behavioral genetics of thermosensation and hygrosensation in Drosophila
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DOI：
10.1073/pnas.93.12.6079
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发表时间：
1996-06-11
影响因子：
11.1
通讯作者：
Benzer, S
中科院分区：
文献类型：
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作者：
Sayeed, O;Benzer, S
虽然温度和湿度是影响生理、行为和进化的关键变量，但温度感觉和湿感觉的遗传和神经元基础仍然知之甚少。我们已经开始了对果蝇这些感觉系统的行为遗传学研究。描述了用于快速筛选在热敏和湿敏方面有缺陷的突变体的行为测试。我们展示了正常果蝇对温度和湿度的强烈反应。有两个突变体在温度感觉上存在缺陷，其中只有一个突变体在湿感上也存在缺陷，这表明它们涉及不同的感觉机制。消融实验进一步分离了这些感觉系统，显示温度感受器位于触角的第三段，而湿感受器位于触角更远的位置。
Whereas temperature and humidity are critical variables affecting physiology, behavior, and evolution, the genetic and neuronal underpinnings of thermosensation and hygrosensation remain poorly understood. We have initiated a behavioral-genetic investigation of these sensory systems in Drosophila. Behavioral tests are described for the rapid screening of mutants defective in thermosensation and hygrosensation. We demonstrate the strong responses of normal flies to temperature and humidity. Two mutants were found with defects in thermosensation, only one of which is also defective in hygrosensation, indicating that they involve different sensory mechanisms. Ablation experiments further separate these sensory systems by showing that thermoreceptors are housed in the third antennal segment, whereas hygroreceptors are located more distally in the antennal arista.