Nutrition and melanoma: the contribution of trace elements in onset, progression, and treatment of melanoma
Nutrition and melanoma: the contribution of trace elements in onset, progression, and treatment of melanoma
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DOI：
10.1093/nutrit/nuad106
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Jinfeng Wu
中科院分区：
文献类型：
--
作者：
Rui Lei;Xiao Liu;Jinfeng Wu
Abstract. Melanoma is a highly malignant and drug-resistant disease that imposes a substantial economic burden on the world. There are many studies linking trace elements to diverse types of cancers, including melanoma. This review elucidates the relationship between trace elements exposure and melanoma. It was identified that copper, manganese, selenium, zinc, iron, and many other trace elements were associated with melanoma in humans. In terms of epidemiology, different elements have different correlations with melanoma. These trace elements affect the occurrence and development of melanoma through various mechanisms, such as oxidative stress and the MAPK pathway. The literature on the role of trace elements in the pathogenesis and treatment of melanoma depicts promising prospects for this field.
