Effects of sleep deprivation on polysomnography and executive function in patients with depression
Effects of sleep deprivation on polysomnography and executive function in patients with depression
复制标题
睡眠剥夺对抑郁症患者多导睡眠图和执行功能的影响
DOI：
10.3760/cma.j.issn.0366-6999.20140665
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发表时间：
2014-09-20
影响因子：
6.1
通讯作者：
Cui Yi
中科院分区：
文献类型：
--
作者：
Lu Yingzhi;Ren Qingtao;Cui Yi
Backgorund睡眠剥夺(SD)已被用于治疗抑郁症，并能有效地改善患者的抑郁症状。为探讨SD对抑郁症患者脑电(EEG)和执行功能的影响。方法18例抑郁症患者(DPS)和21例健康对照(HCS)。采用Neurofax-1518K(Nihon Kohden，日本)系统记录SD大鼠36小时的整夜多导睡眠图(PSG)。用视觉模拟评定量表(VAS)评定抑郁程度，威斯康星卡片分类测验(WCST)评定执行功能。结果睡眠潜伏期(SL)显著降低(SD前：(31.8±11.1)分钟，SD后：(8.8±5.2)分钟，P
Backgorund Sleep deprivation (SD) has been used in treatment of depression disorder, and could effectively improve the patients' depressive symptoms. The aim of the study was to explore the effects of SD on electroencephalographic (EEG) and executive function changes in patients with depression.Methods Eighteen depression patients (DPs) and 21 healthy controls (HCs) were enrolled in the present study. The whole night polysomnography (PSG) was recorded by Neurofax-1518K (Nihon Kohden, Japan) system before and after 36 hours of SD. The level of subjects' depression state was assessed by Visual Analogue Scale (VAS), and the executive function was assessed by Wisconsin Card Sorting Test (WCST).Results Significantly decreased sleep latency (SL; before SD: (31.8 +/- 11.1) minutes, after SD: (8.8 +/- 5.2) minutes, P