The economic value of a quadrivalent versus trivalent influenza vaccine.

The economic value of a quadrivalent versus trivalent influenza vaccine.
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DOI:
10.1016/j.vaccine.2012.10.025
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发表时间:
2012-12-14
期刊:
影响因子:
5.5
通讯作者:
Willig, Alyssa M.
Willig, Alyssa M.
中科院分区:
医学3区
文献类型:
--
作者:
Lee, Bruce Y.;Bartsch, Sarah M.;Willig, Alyssa M.

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最近获得许可的四价季节性流感疫苗(QIV)可能比传统的三价流感疫苗(TIV)提供更好的保护,因为它多了一种乙型流感病毒株。我们开发了蒙特卡罗模拟模型,以确定十个流感季节(1999-2009)QIV 与 TIV 相比的经济价值。添加乙型流感毒株将 TIV 转化为 QIV 可能会为社会(中位数为 31 亿美元)和第三方付款人(中位数为 2.92 亿美元)节省大量成本,即使 QIV 的成本要高得多
The recently licensed quadrivalent seasonal influenza vaccine (QIV) may provide better protection than the traditional trivalent influenza vaccine (TIV) as it includes one more influenza B strain. We developed a Monte Carlo simulation model to determine the economic value of a QIV compared to the TIV for ten influenza seasons (1999–2009). The addition of the influenza B strain to convert the TIV into a QIV could result in substantial cost savings to society (median of $3.1 billion) and third party payers (median of $292 million), even when the cost of QIV is significantly higher
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发表时间: 2010-09-07
期刊: VACCINE
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