ACTIVATION OF EXTRASTRIATE AND FRONTAL CORTICAL AREAS BY VISUAL WORDS AND WORD-LIKE STIMULI
ACTIVATION OF EXTRASTRIATE AND FRONTAL CORTICAL AREAS BY VISUAL WORDS AND WORD-LIKE STIMULI
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DOI：
10.1126/science.2396097
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发表时间：
1990-08-31
期刊：
影响因子：
56.9
通讯作者：
RAICHLE, ME
中科院分区：
文献类型：
--
作者：
PETERSEN, SE;FOX, PT;RAICHLE, ME
单词的视觉呈现会激活大脑枕叶的纹外区域。当通过正电子发射断层扫描（PET）进行分析时，左侧内侧外纹视觉皮层的某些区域被视觉呈现的遵守英语拼写规则的伪单词以及实际单词激活。这些区域不会被无意义的字母串或类似字母的形式激活。因此，视觉词形计算基于学习到的单词和非单词之间的区别。此外，在被动呈现单词（而非伪单词）期间，激活发生在与语义处理相关的左额叶区域。这些发现支持认知心理学和计算建模中对单个单词的高级视觉和语义计算之间的区别，并描述了这些区别背后可能存在的解剖结构。
Visual presentation of words activates extrastriate regions of the occipital lobes of the brain. When analyzed by positron emission tomography (PET), certain areas in the left, medial extrastriate visual cortex were activated by visually presented pseudowords that obey English spelling rules, as well as by actual words. These areas were not activated by nonsense strings of letters or letter-like forms. Thus visual word form computations are based on learned distinctions between words and nonwords. In addition, during passive presentation of words, but not pseudowords, activation occurred in a left frontal area that is related to semantic processing. These findings support distinctions made in cognitive psychology and computational modeling between high-level visual and semantic computations on single words and describe the anatomy that may underlie these distinctions.