PROJECTIONS TO INFERIOR OLIVE OF CAT .1. COMPARISONS OF INPUT FROM DORSAL COLUMN NUCLEI, LATERAL CERVICAL NUCLEUS, SPINO-OLIVARY PATHWAYS, CEREBRAL-CORTEX AND CEREBELLUM
PROJECTIONS TO INFERIOR OLIVE OF CAT .1. COMPARISONS OF INPUT FROM DORSAL COLUMN NUCLEI, LATERAL CERVICAL NUCLEUS, SPINO-OLIVARY PATHWAYS, CEREBRAL-CORTEX AND CEREBELLUM
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DOI：
10.1002/cne.901800204
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发表时间：
1978-01-01
影响因子：
2.5
通讯作者：
WORDEN, IG
中科院分区：
文献类型：
--
作者：
BERKLEY, KJ;WORDEN, IG
本实验比较了猫的背柱核(DCN)、颈外侧核(LCN)、棘橄榄通路(SO)、运动皮质(MS1)和小脑(CB)向下橄榄核的投射。差异标记策略被用于这些比较。对侧DCN和LCN的投射与同侧DCN和LCN的投射在下橄榄的背侧附属部和内侧副橄榄的尾侧半部广泛重叠。来自对侧运动皮质的投射部分与这些躯体感觉投射重叠，但它们也延伸到主部和内侧副橄榄核的吻侧半部，在那里其他投射来自其他运动来源，如红核、苍白球和尾状核。对侧小脑主要投射到下橄榄核的大部分，除了两个副核的尾侧部分的少数区域。在下橄榄内，躯体感觉和运动输入之间存在部分分离，小脑反馈纤维似乎至少避开了那些躯体感觉输入较重的区域的一部分。一些这种分离，特别是在内侧副橄榄核和主要核，与橄榄-小脑连接和这些区域的细胞结构的差异有关。尽管躯体感觉和运动输入是部分分离的，但这些输入也有几个区域重叠。这些区域是：在背副橄榄吻部的内侧半部分的区域，和在内侧副橄榄的尾侧半部分中间的一个小椭圆形区域。这种重叠为电生理学证据提供了解剖学基础，该证据表明在这些区域中的一些区域存在对大脑皮层和脊髓的激活做出反应的细胞。
The present experiments compare the projections from the dorsal column nuclei (DCN), the lateral cervical nucleus (LCN), the spino-olivary pathways (SO), the motor cortex (Ms1) and the cerebellum (CB) to the inferior olive of the cat. A differential labeling strategy was used for these comparisons. Projections from the contralateral DCN and LCN and the ipsilateral SO overlap extensively with each other in the dorsal accessory division of the inferior olive and the caudal half of the medial accessory olive. Projections from the contralateral motor cortex partially overlap these somato-sensory projections but they also extend into the principal division and into the rostral half of the medial accessory olive where others have found input from other motor sources such as the red n. [nucleus], the globus pallidus and the caudate n. The contralateral cerebellum projects heavily to most of the inferior olive except for a few regions in the caudal portions of the 2 accessory nuclei. There is a partial segregation between somatosensory and motor inputs within the inferior olive and the cerebellar feedback fibers appear to avoid at least parts of those regions where the somatosensory input is heavy. Some of this segregation, particularly within the medial accessory olive and the principal n., correlates with differences in both the olivo-cerebellar connectivity and the cytoarchitecture of these regions. Although the somatosensory and motor inputs are partially segregated, there are also several regions where these inputs overlap. These regions are: an area in the medial half of the rostral portions of the dorsal accessory olive, and a small oval zone in the middle of the caudal half of the medial accessory olive. This overlap provides an anatomical basis for electrophysiological evidence which demonstrates the existence of cells in some of these regions that respond to activation of both the cerebral cortex and the spinal cord.