ATPASE AS AN IRREVERSIBLE COMPONENT IN ELECTRON-TRANSPORT LINKED ATP SYNTHESIS
ATPASE AS AN IRREVERSIBLE COMPONENT IN ELECTRON-TRANSPORT LINKED ATP SYNTHESIS
复制标题
DOI：
10.1016/0014-5793(76)80073-7
复制
发表时间：
1976-01-01
期刊：
影响因子：
3.5
通讯作者：
WHATLEY, FR
中科院分区：
文献类型：
--
作者：
FERGUSON, SJ;JOHN, P;WHATLEY, FR
参与氧化磷酸化的 ATP 酶的可逆性隐含在磷酸盐电位（储存在 ATP 中的能量）与呼吸链达到平衡的想法中 [1]。这是呼吸控制解释的基础，其中 ADP 刺激的呼吸（状态 3）持续直至达到平衡，随后呼吸降低至受控速率（状态 4）。我们在本文中的目的是通过考虑具有呼吸控制功能的脱氮嘌呤菌的“由内而外”磷酸化膜囊泡的氧化磷酸化装置的特性来探讨这种平衡观点是否总是正确的[2,3,4]。
The reversibility of the ATPase that participates in oxidative phosphorylation is implicit within the idea that the phosphate potential (energy stored in ATP) comes into equilibrium with the respiratory chain [1]. This is the basis of an explanation of respiratory control in which ADP stimulated respiration (state 3) continues until this equilibrium is reached, whereupon respiration decreases to a controlled rate (state 4). Our purpose in this paper is to enquire whether this equilibrium view is always correct by considering the properties of the oxidative phosphorylation apparatus of ‘inside out’phosphorylating membrane vesicles from Puracoccus denitrificans which exhibit respiratory control [2, 3, 4].