Correlation between the ABC classification and radiological findings for assessing gastric cancer risk
Correlation between the ABC classification and radiological findings for assessing gastric cancer risk
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ABC 分类与评估胃癌风险的放射学结果之间的相关性
DOI：
10.1007/s11604-015-0469-3
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发表时间：
2015
影响因子：
2.1
通讯作者：
K. Kichikawa
中科院分区：
文献类型：
--
作者：
T. Itoh;M. Saito;N. Marugami;T. Hirai;Aki Marugami;J. Takahama;Toshihiro Tanaka;K. Kichikawa
目的探讨ABC风险评估与胃粘膜影像学表现的相关性，提出一种改进的胃癌筛查方法。材料与方法对318名受试者进行幽门螺杆菌（Hp）抗体滴度、血清胃蛋白酶原（PG）和上消化道x线检查，并将其分为3组：A组，双阴性；B， hp阳性，pg阴性；C, PG-positive。A组分为：A-1组，Hp抗体滴度<3.0 U/ml；A-2， Hp抗体滴度≥3.0 U/ml。回顾性分析A组和非A组（B或C组）参与者的结果和胃粘膜（褶皱和胃区）的影像学表现。结果A-1组207例与非a组98例放射学表现差异显著。褶皱分布的优势比为17.72，褶皱厚度的优势比为10.63，褶皱特征的优势比为6.10，胃面积的优势比为10.62。≥2个危险因素的存在提供了90.3%的敏感性，94.7%的特异性和93.3%的准确性。放射学结果显示，13名a -2组参与者中有9名（69.2%）和11名（5.3%）a -1组参与者有胃癌风险。结论ABC分类与胃癌的影像学表现有较好的相关性，但也存在差异。我们推荐这两种方法作为胃癌的筛查。
PurposeTo investigate the correlation between ABC risk assessment and radiological findings of gastric mucosa and to propose an improved method for gastric cancer screening.Materials and MethodsWe evaluated 318 participants withHelicobacter pylori(Hp) antibody titers, serum pepsinogen (PG) and upper GI radiography and then classified them into three groups: A, double-negative; B, Hp-positive, PG-negative; C, PG-positive. Group A was subclassified as: A-1, Hp antibody titer <3.0 U/ml; A-2, Hp antibody titer ≥3.0 U/ml. Results for group A and non-A (B or C) participants and radiological findings of gastric mucosa (fold and area gastricae) were analyzed retrospectively.ResultsRadiological findings differed significantly between the 207 A-1 and 98 non-A group. Odds ratios were 17.72 for fold distribution, 10.63 for fold thickness, 6.10 for fold characteristics, and 10.62 for area gastricae. Presence of ≥2 risk factors offered 90.3 % sensitivity, 94.7 % specificity, and 93.3 % accuracy. Nine (69.2 %) of the 13 A-2 group participants and 11 (5.3 %) A-1 group participants had a risk for gastric cancer according to radiological findings.ConclusionA good correlation exists between ABC classifications and radiological findings for gastric cancer risk, but some discrepant cases exist. We recommend both methods as screening for gastric cancer.
影响因子：
3.1
作者：
Mizuno, Shigeto;Miki, Ikuya;Watanabe, Yoshiyuki
通讯作者：
Watanabe, Yoshiyuki
影响因子：
6.4
作者：
Ohata, H;Kitauchi, S;Ichinose, M
通讯作者：
Ichinose, M
影响因子：
2.4
作者：
Hamashima, Chisato;Shibuya, Daisuke;Sobue, Tomotaka
通讯作者：
Sobue, Tomotaka