Immunocytochemical localization of human papilloma virus and cytomorphologic correlation in smears and biopsies of cervical flat condylomata
Immunocytochemical localization of human papilloma virus and cytomorphologic correlation in smears and biopsies of cervical flat condylomata
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宫颈扁平湿疣涂片和活检中人乳头瘤病毒的免疫细胞化学定位和细胞形态学相关性
DOI:
10.1002/dc.2840020410
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发表时间:
1986
影响因子:
1.3
通讯作者:
M. Hutchinson
中科院分区:
文献类型:
--
作者:
H. Deligeorgi‐Politi;K. K. Mui;K. Trotta;H. Safaii;S. H. An;H. Wolfe;M. Hutchinson
The cytomorphologic features in cervical biopsies and smears associated with human papilloma virus antigen (Ag) expression as demonstrated by immunoperoxidase staining techniques are presented. There was good concordance between cytology and biopsy results with respect to immunoperoxidase staining for human papilloma virus Ag. Cytomorphologic scoring of low‐grade lesions (cervical intraepithelial neoplasias, grades 0 and I) showed atypical mitoses, macronucleated koilocytes, superficial cell keratohyaline granules, and multinucleation to be more frequent in Ag+ biopsy specimens. Chronic inflammation was more evident in Ag‐ biopsy specimens (P < 0.05). Parakeratosis was more frequent in Ag+ cytologic specimens. Koilocytosis was not a reliable indicator of Ag expression in either preparation. Human papilloma virus (HPV) Ag testing by immunoperoxidase techniques appears to be a useful adjunct for screening low‐grade atypias of the cervix. Diagn Cytopathol 1986;2:320‐325.
影响因子:
7.2
作者:
Fujii,T;Crum,CP;Winkler,B;Fu,YS;Richart,RM
通讯作者:
Richart,RM
影响因子:
7.2
作者:
Woodruff,JD;Braun,L;Cavalieri,R;Gupta,P;Pass,F;Shah,KV
通讯作者:
Shah,KV
DOI:
--
发表时间:
1981
期刊:
Journal of the National Cancer Institute
影响因子:
--
作者:
Morin,C;Braun,L;Casas-Cordero,M;Shah,KV;Roy,M;Fortier,M;Meisels,A
通讯作者:
Meisels,A