BeoBLAST: Distributed BLAST and PSI-BLAST on a beowulf cluster

BeoBLAST: Distributed BLAST and PSI-BLAST on a beowulf cluster
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DOI:
10.1093/bioinformatics/18.5.765
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发表时间:
2002-05-01
期刊:
影响因子:
5.8
通讯作者:
Ochs, MF
Ochs, MF
中科院分区:
生物学3区
文献类型:
--
作者:
Grant, JD;Dunbrack, RL;Ochs, MF

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BeoBLAST是一个集成软件包,可处理用户请求并将BLAST和PSI-BLAST搜索分发到Beowulf集群的节点,从而提供了一种在相对便宜的计算机集群上实现可扩展BLAST系统的简单方法。此外,BeoBLAST还通过其网络界面提供了许多新颖的搜索功能,包括通过多个查询同时搜索多个数据库的功能,以及使用先前在不同数据库上进行PSI-BLAST搜索生成的PSSM启动搜索的功能。底层系统还可以处理高吞吐量工作的自动查询。
BeoBLAST is an integrated software package that handles user requests and distributes BLAST and PSI-BLAST searches to nodes of a Beowulf cluster, thus providing a simple way to implement a scalable BLAST system on top of relatively inexpensive computer clusters. Additionally, BeoBLAST offers a number of novel search features through it's web interface, including the ability to perform simultaneous searches of multiple databases with multiple queries, and the ability to start a search using the PSSM generated from a previous PSI-BLAST search on a different database. The underlying system can also handle automated querying for high throughput work.