Resting State Functional MR Imaging of Language Function.
Resting State Functional MR Imaging of Language Function.
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DOI：
10.1016/j.nic.2020.09.005
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发表时间：
2021-03
影响因子：
2.3
通讯作者：
Shimony JS
中科院分区：
文献类型：
--
作者：
Lee JJ;Luckett P;Fakhri MM;Leuthardt EC;Shimony JS
使用基于任务的功能性MR成像（T-fMR成像）定位语言区域目前被认为是在手术切除可能影响大脑的这些关键区域（“功能皮层”）的大脑病变之前的护理标准。1这些信息对于术前计划、发病风险评估以及与患者及其家属的协商至关重要。这种方法最常用于脑肿瘤切除术，但在许多其他神经外科手术中也很常见，如癫痫手术、脑活检和激光消融手术。准确地映射语言功能受到多种因素的影响，如语言系统的众多组成部分（接受性与表达性语言、记忆、阅读、听力和口语，涉及视觉、听觉和运动系统的组成部分），2和变异性，其位置在患者之间，即使在半球优势建立。使手术计划更加复杂的是，需要在积极切除（可以延长生命和延迟复发）和功能保留（降低发病率）之间整合这些信息，3-5这可能取决于肿瘤相对于语言系统不同部分的确切位置。语言系统的某些区域不会从切除中恢复（例如，布罗卡区），但其他区域可能在恢复时间和治疗后完全恢复（例如，辅助运动区）。6
Localization of language regions using task-based functional MR imaging (T-fMR imaging) is currently considered standard of care before surgical resection of brain lesions that may impinge on these critical areas of the brain (“eloquent cortex”). 1 This information is considered critical for presurgical planning, assessing the risk for morbidity, and consultation with patients and their families. This method is most often used for brain tumor resection, but has become common in numerous other neurosurgical procedures such as epilepsy surgery, brain biopsies, and laser ablation procedures.Mapping language function accurately is complicated by several factors such as the numerous components of the language system (receptive vs expressive language, memory, reading, listening, and speaking that involve components of vision, hearing, and the motor systems), 2 and the variability of its location across patients even after hemispheric dominance is established. Further complicating the surgical plan is the need to integrate this information between aggressive resection (that can extend life and delay recurrence) and functional preservation (decreasing morbidity), 3–5 which can differ depending on the exact location of the tumor with respect to different parts of the language system. Some areas of the language system will not recover from resection (eg, Broca’s area), but others may be fully restored after recovery time and therapy (eg, supplementary motor area). 6
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影响因子：
3.7
作者：
Leuthardt, Eric C.;Guzman, Gloria;Benzinger, Tammie L. S.
通讯作者：
Benzinger, Tammie L. S.
影响因子：
5.7
作者：
Hacker CD;Laumann TO;Szrama NP;Baldassarre A;Snyder AZ;Leuthardt EC;Corbetta M
通讯作者：
Corbetta M
影响因子：
4.1
作者：
Lacroix, M;Abi-Said, D;Sawaya, R
通讯作者：
Sawaya, R
影响因子：
6
作者：
Blei, DM;Ng, AY;Jordan, MI
通讯作者：
Jordan, MI
影响因子：
1.8
作者：
Rivest, J;Cavanagh, P
通讯作者：
Cavanagh, P