Case-control studies: basic concepts

Case-control studies: basic concepts
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DOI:
10.1093/ije/dys147
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发表时间:
2012-10-01
影响因子:
7.7
通讯作者:
Pearce, Neil
Pearce, Neil
中科院分区:
医学1区
文献类型:
--
作者:
Vandenbroucke, Jan P.;Pearce, Neil

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本文的目的是用基本的数学和统计学术语介绍一种快速有效地教授和理解病例对照研究的简单方法,就像它们在动态人群中通常所做的那样--而不使用罕见疾病假设。我们的重点是疾病发病率的病例对照研究(“事件病例对照研究”);我们不会考虑流行疾病的病例对照研究的情况,因为这些研究发表的频率要少得多。
The purpose of this article is to present in elementary mathematical and statistical terms a simple way to quickly and effectively teach and understand case-control studies, as they are commonly done in dynamic populations-without using the rare disease assumption. Our focus is on case-control studies of disease incidence ('incident case-control studies'); we will not consider the situation of case-control studies of prevalent disease, which are published much less frequently.