Circannual body weight rhythms of ground squirrels: role of gonadal hormones.
Circannual body weight rhythms of ground squirrels: role of gonadal hormones.
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地松鼠的体重节律：性腺激素的作用。
DOI：
10.1152/ajpregu.1982.243.5.r546
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发表时间：
1982
期刊：
影响因子：
--
通讯作者：
Boshes,M
中科院分区：
文献类型：
--
作者：
Zucker,I;Boshes,M
在23 ℃、LD为14：10的光照条件下，研究了卵巢和睾丸激素对金背黄鼠（Spermophilus lateralis）体重年周期的影响。在47日龄时对动物进行性腺切除或假手术，并植入空胶囊或填充有苯甲酸雌二醇（EB）或丙酸睾酮（TP）的胶囊。每周记录一次体重、摄食量和生殖状况。性腺切除和完整的松鼠的两性表现出强大的circannual节奏的体重，周期性分泌的性腺激素是没有必要的表达这个circannual周期。完整的和性腺切除男性的体重大大超过他们的女性同行，但只有在部分年度周期。这种性别差异在没有同时性腺激素分泌的情况下，在一个昼夜的基础上增加和减少。EB阶段延迟达到峰值体重卵巢切除松鼠，但不影响时间的低谷体重。EB增加了卵巢切除松鼠的食物消耗量，特别是在体重增加阶段。TP加速了去卵巢动物达到谷体重。性腺激素改变体重波峰和波谷的大小和时间，但对于体重年周期的产生或表达或该周期中的性别差异不是必需的。
The influence of ovarian and testicular hormones on circannual body weight cycles was assessed in golden-mantled ground squirrels (Spermophilus lateralis), maintained in a LD 14:10 photoperiod at 23 degrees C. Animals were gonadectomized or sham operated at 47 days of age and implanted with empty capsules or capsules filled with estradiol benzoate (EB) or testosterone propionate (TP). Body weight, food intake, and reproductive condition were recorded at weekly intervals. Gonadectomized and intact squirrels of both sexes manifested robust circannual rhythms of body weight; cyclic secretion of gonadal hormones was not necessary for the expression of this circannual cycle. Intact and gonadectomized males weighed substantially more than their female counterparts but only during part of the annual cycle. This sex difference waxed and waned on a circannual basis in the absence of concurrent gonadal hormone secretions. EB phase-delayed attainment of peak body weights in ovariectomized squirrels but did not affect timing of trough body weights. EB increased the amount of food consumed by ovariectomized squirrels particularly during the weight gain phase. TP accelerated attainment of trough body weights in orchidectomized animals. Gonadal hormones modify the magnitude and timing of body weight peaks and troughs but are not necessary for the generation or expression of the circannual body weight cycle or for the sex difference in this cycle.