The epidemiology of narcolepsy in Olmsted County, Minnesota: A population-based study
The epidemiology of narcolepsy in Olmsted County, Minnesota: A population-based study
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DOI：
10.1093/sleep/25.2.197
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发表时间：
2002-03-15
期刊：
影响因子：
5.6
通讯作者：
Pankratz, VS
中科院分区：
文献类型：
--
作者：
Silber, MH;Krahn, LE;Pankratz, VS
研究目的：为了确定特定年龄和性别的发病率和发作性睡病的患病率在美国community.Design：记录联动系统的罗切斯特流行病学项目被用来确定所有的发作性睡病患者在奥姆斯特德县，明尼苏达州1960年至1989年。使用人口普查数据计算了特定年龄和性别的发病率。计算1985年1月1日发作性睡病的患病率。设置.不适用患者或参与者。社区患者诊断为发作性睡病的一套有效的诊断标准。干预措施：N/A测量和结果：发病率每10万人每年为1.37（男性1.72，女性1.05）。发病率以第2个10年最高，依次为第3、4、10年。1985年1月1日的患病率为每10万人56.3人。大约36%的患病率病例没有cataploids.Conclusions：发作性睡病是不是一种罕见的疾病。它似乎在男性中更常见。它最常见于第二个十年。无惊厥发作性睡病是一个重要的亚群，有待进一步研究。
Study Objectives: To determine the age- and sex-specific incidence rates and prevalence of narcolepsy in a United States community.Design: The records-linkage system of the Rochester Epidemiology Project was utilized to ascertain all patients with narcolepsy seen in Olmsted County, Minnesota between 1960 and 1989. Age- and sex-specific incidence rates were calculated, using census data. Prevalence of narcolepsy on January 1, 1985 was calculated. Setting. N/A Patients or Participants. Community patients diagnosed with narcolepsy by a validated set of diagnostic criteria.Interventions: N/AMeasurements and Results: The incidence rate per 100,000 persons per year was 1.37 (1.72 for men and 1.05 for women). The incidence rate was highest in the 2nd decade, followed in descending order by the 3rd, 4th and list decades. The prevalence on January 1, 1985 was 56.3 per 100,000 persons. Approximately 36% of prevalence cases did not have cataplexy.Conclusions: Narcolepsy is not a rare disorder. It appears to be commoner in men. It originates most commonly in the 2nd decade. Narcolepsy without cataplexy is an important subgroup, warranting further study.