Correlation of regional cerebral blood flow and change of plasma sodium concentration during genesis and satiation of thirst
Correlation of regional cerebral blood flow and change of plasma sodium concentration during genesis and satiation of thirst
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DOI：
10.1073/pnas.96.5.2532
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发表时间：
1999-03-02
影响因子：
11.1
通讯作者：
Fox, P
中科院分区：
文献类型：
--
作者：
Denton, D;Shade, R;Fox, P
在快速静脉注射高渗生理盐水（0.51 M）引起中度口渴和饮水解渴时进行正电子发射断层扫描研究。区域脑血流与血浆钠浓度变化的相关性显示，在前扣带区、颞中回和导水管周围灰质也有明显的脑激活。最强烈的失活发生在海马旁和额回。这些数据与前扣带在口渴发生中的重要作用是一致的。
Positron emission tomography studies were conducted during genesis of moderate thirst by rapid i.v. infusion of hypertonic saline (0.51 M) and after satiation of thirst by drinking water. The correlation of regional cerebral blood flow with the change in the plasma Na concentration showed a significant group of cerebral activations in the anterior cingulate region and also a site in the middle temporal gyrus and in the periaqueductal gray. Strongest deactivations occurred in the parahippocampal and frontal gyri. The data are consistent with an important role of the anterior cingulate in the genesis of thirst.