Fish Gelatin: Current Nutritional, Medicinal, Tissue Repair Applications and Carrier of Drug Delivery.
Fish Gelatin: Current Nutritional, Medicinal, Tissue Repair Applications and Carrier of Drug Delivery.
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鱼明胶：当前的营养、药用、组织修复应用和药物输送载体。
DOI：
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发表时间：
2022
影响因子：
3.1
通讯作者：
Srijit Das
中科院分区：
文献类型：
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作者：
Amro M. Soliman;S. Teoh;Srijit Das
明胶是通过胶原蛋白的部分变性获得的，广泛用于各种工业。全球使用的大部分明胶来自哺乳动物来源。报告了与猪/牛明胶相关的几个健康和宗教问题。因此，来自海洋来源的明胶作为猪/牛明胶的潜在替代品在各种应用中的效率和利用率正在被广泛研究。虽然鱼明胶是不太耐用，并具有较低的熔化和胶凝温度相比，哺乳动物来源的明胶，各种修改正在报道，以促进其流变学和功能特性，以有效地利用。本综述详细介绍了目前鱼明胶的创新应用，涉及食品工业，药物输送和可能的治疗应用。明胶生物活性分子可用作药物递送的载体。由于其多功能性，明胶可用于不同的载体系统，如微粒，纳米颗粒，纤维和水凝胶。本综述还提供了对其他潜在的药物应用的鱼明胶，如组织再生，抗氧化剂的补充，抗高血压和抗癌治疗的前景。
Gelatin is obtained via partial denaturation of collagen and is extensively used in various industries. The majority of gelatin utilized globally is derived from a mammalian source. Several health and religious concerns associated with porcine/bovine gelatin were reported. Therefore, gelatin from a marine source is widely being investigated for its efficiency and utilization in a variety of applications as a potential substitute for porcine/bovine gelatin. Although fish gelatin is less durable and possesses lower melting and gelling temperatures compared to mammal-derived gelatin, various modifications are being reported to promote its rheological and functional properties to be efficiently employed. The present review describes in detail the current innovative applications of fish gelatin involving the food industry, drug delivery and possible therapeutic applications. Gelatin bioactive molecules may be utilized as carriers for drug delivery. Due to its versatility, gelatin can be used in different carrier systems, such as microparticles, nanoparticles, fibers and hydrogels. The present review also provides a perspective on the other potential pharmaceutical applications of fish gelatin, such as tissue regeneration, antioxidant supplementation, antihypertensive and anticancer treatments.