Incontinence Improves in Older Women After Intensive Pelvic Floor Muscle Training: An Assessor-Blinded Randomized Controlled Trial

Incontinence Improves in Older Women After Intensive Pelvic Floor Muscle Training: An Assessor-Blinded Randomized Controlled Trial
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DOI:
10.1002/nau.20968
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发表时间:
2011-01-01
影响因子:
2
通讯作者:
Galea, Mary P.
Galea, Mary P.
中科院分区:
医学3区
文献类型:
--
作者:
Sherburn, Margaret;Bird, Margaret;Galea, Mary P.

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目的:验证高强度盆底肌训练(PFMT)对社区老年妇女压力性尿失禁有效的假设,并且在该人群中,高强度PFMT比膀胱训练(BT)更能改善压力性尿失禁。方法:采用双中心、评估者盲法随机对照试验,为期20周,采用PFMT和BT两种主动干预方式,在两家大城市三级医院进行评估和干预。参与者为65岁以上尿动力应激性尿失禁的社区妇女。主要结局指标为咳嗽压力试验期间尿漏。次要结局指标包括症状和烦恼(ICIQ-UI SF)、参与者总体变化感知、泄漏事件(7天事故日记)、“烦恼”程度(VAS)和健康相关生活质量(aol)。结果:83名高加索女性,71.8 (SD 5.3)岁。两组在干预期间均有所改善;然而,PFMT组在压力测试中报告的渗漏量明显较低[PFMT中位数0.0 g, 95% CI: 0.2-0.9;BT中位数0.3 g, 95% CI: 0.2 ~ 1.7, P=0.006],改善症状和烦恼[PFMT平均5.9,95% CI: 4.8 ~ 7.1;BT组平均8.5,95% CI: 7.1-9.9和更大的变化感知[PFMT 28 (73.6%)];bt12组(36.4%)(P=0.002)在5个月后明显低于bt12组。结论:高强度PFMT治疗老年健康女性压力性尿失禁有效,且效果优于BT。Neurourol。中国生物医学工程学报,2011,30(3):317-324。(C) 2011 Wiley-Liss, Inc。
Aims: To test the hypotheses that high intensity pelvic floor muscle training (PFMT) is effective in relief of stress urinary incontinence in community dwelling older women, and that intense PFMT improves stress urinary incontinence more than bladder training (BT) in this population. Methods: A two-center, assessor-blinded randomized controlled trial of 20 weeks duration with two active intervention arms: PFMT and BT. Assessments and interventions were undertaken at two metropolitan tertiary hospitals. Participants were community dwelling women over 65 years of age with urodynamic stress incontinence. Primary outcome measure was urinary leakage during a cough stress test. Secondary outcome measures included symptoms and bother (ICIQ-UI SF), participant global perception of change, leakage episodes (7-day accident diary), degree of "bother" (VAS) and health related quality of life (AQoL). Results: Eighty-three Caucasian women, 71.8 (SD 5.3) years participated in the study. Both groups improved over the intervention period; however, the PFMT group reported significantly lower amounts of leakage on the stress test [PFMT median 0.0 g, 95% CI: 0.2-0.9; BT median 0.3 g, 95% CI: 0.2-1.7, P=0.006], improved symptoms and bother [PFMT mean 5.9, 95% CI: 4.8-7.1; BT group mean 8.5, 95% CI: 7.1-9.9 and greater perception of change [PFMT 28 (73.6%); BT 12 (36.4%) (P=0.002)] after 5 months than the BT group. Conclusions: High intensity PFMT is effective in managing stress urinary incontinence and is more effective than BT in healthy older women. Neurourol. Urodynam. 30: 317-324, 2011. (C) 2011 Wiley-Liss, Inc.