Pharyngeal swallowing: Defining pharyngeal and upper esophageal sphincter relationships in human neonates
Pharyngeal swallowing: Defining pharyngeal and upper esophageal sphincter relationships in human neonates
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DOI：
10.1016/j.jpeds.2007.04.042
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发表时间：
2007-12-01
影响因子：
5.1
通讯作者：
Shaker, Reza
中科院分区：
文献类型：
--
作者：
Jadcherla, Sudarshan Rao;Gupta, Alankar;Shaker, Reza
目的通过研究咽部刺激对健康新生儿咽部-上食管括约肌（UES）相互作用的影响，验证空气和水注入刺激诱发的反射的感觉运动特征不同的假设。给予咽部输注空气（0.1至2.0 mL）和无菌水（0.1至0.5 mL）（n = 155）。识别出两种类型的反射：咽反射性吞咽（PRS）和咽-UES-收缩反射（PUCR）。结果对空气和水的反射反应率分别为30%和76%（P
Objective To test the hypothesis that the sensorimotor characteristics of the reflexes evoked on stimulation with air and water infusions differ by studying the effect of pharyngeal stimulation on pharyngeal-upper esopliageal sphincter (UES) interactions in healthy neonates.Study design Pharyngo-UES-esophageal manometry was recorded in 10 neonates at 39 +/- 4 weeks postmenstrual age. Pharyngeal infusions (n = 155) of air (0.1 to 2.0 mL) and sterile water (0.1 to 0.5 mL) were given. Two types of reflexes were recognized: pharyngeal reflexive swallowing (PRS) and pharyngo-UES-contractile reflex (PUCR). Frequency occurrence, distribution of reflexes, threshold volume, response time, and stimulus-response relationship were evaluated.Results The reflex response rates were 30% for air and 76% for water (P