Colorectal cancer incidence in Asian migrants to the United States and their descendants
Colorectal cancer incidence in Asian migrants to the United States and their descendants
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DOI：
10.1023/a:1008955722425
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发表时间：
2000-05-01
影响因子：
2.3
通讯作者：
Potter, JD
中科院分区：
文献类型：
--
作者：
Flood, DM;Weiss, NS;Potter, JD
目的：根据出生国家调查美国亚裔居民结直肠癌的发病率。方法：我们确定了 1973 年至 1986 年间美国西部三个地区（夏威夷、旧金山/奥克兰 SMSA 和华盛顿州西部）亚裔居民结直肠癌的发病率与出生国家的关系。比率分子来自监测、流行病学和最终结果 (SEER) 计划；使用 1980 年美国人口普查的特殊表格来估计高危人口的规模和构成。结果：美国出生的日本男性的结直肠癌发病率是外国出生的日本男性的两倍，比美国出生的白人男性高出约 60%。美国出生的日本女性的发病率比日本出生的日本女性或美国出生的白人女性高出约 40%。外国出生的中国男性的结直肠癌发病率与美国出生的白人男性大致相同，而美国出生的中国男性的发病率略有下降。无论出生地如何，中国女性的患病率普遍比美国出生的白人女性低 30-40%。美国出生和外国出生的菲律宾人的发病率是美国出生的白人的 20-50%。结论：这些研究结果表明，日本移民及其后代之间的一种或多种不同的暴露或特征会影响结直肠癌的发生。
Objectives: To examine the incidence of colorectal cancer among Asian residents of the United States according to country of birth.Methods: We determined the incidence of colorectal cancer during 1973-1986 among Asian residents in three areas of the western United States (Hawaii, San Francisco/Oakland SMSA, and western Washington state) in relation to country of birth. Numerators for the rates were obtained from the Surveillance, Epidemiology and End Results (SEER) program; a special tabulation of the 1980 US Census was used to estimate the size and composition of the population at risk.Results: US-born Japanese men experienced incidence rates of colorectal cancer twice as high as foreign-born Japanese men and about 60% higher than those of US-born white men. Incidence among US-born Japanese women was about 40% higher than that among Japanese women born in Japan or US-born white women. Foreign-born Chinese men had about the same incidence of colorectal cancer as US-born white men, while US-born Chinese men experienced slightly reduced rates. Chinese women had rates that were generally 30-40% lower than that of US-born white women, regardless of place of birth. Incidence rates for both US-born and foreign-born Filipinos were 20-50% those of US-born whites.Conclusions: These findings suggest that one or more exposures or characteristics that differ between Japanese migrants and their descendants affect the development of colorectal cancer.