Dry eyes and corneal sensation after laser in situ keratomileusis with femtosecond laser flap creation Effect of hinge position, hinge angle, and flap thickness
Dry eyes and corneal sensation after laser in situ keratomileusis with femtosecond laser flap creation Effect of hinge position, hinge angle, and flap thickness
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DOI：
10.1016/j.jcrs.2009.07.009
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发表时间：
2009-12-01
影响因子：
2.8
通讯作者：
Shtein, Roni M.
中科院分区：
文献类型：
--
作者：
Mian, Shahzad I.;Li, Amy Y.;Shtein, Roni M.
目的：确定飞秒激光近视准分子激光原位角膜磨镶术(LASIK)术后的角膜知觉和干眼体征及症状是否受不同铰链位置、铰链角度或角膜瓣厚度的影响。研究背景：美国密歇根州安娜堡的大学学术实践。方法：这项前瞻性的随机对侧眼研究评估了双眼近视LASIK术后的眼睛。比较上、颞侧铰链位置、45度和90度铰链角、100微米和130微米角膜瓣厚度。术后1周、1、3、6和12个月的随访包括中心Cochet-Bonnet感觉仪、眼表疾病指数问卷、麻醉下的Schirmer试验、泪膜破裂时间(TBUT)、角膜荧光素染色和结膜李萨明绿染色。结果：本研究评估了95例190只眼。术后所有患者的角膜知觉均降低，术后12个月角膜知觉均有改善(P
PURPOSE: To determine whether corneal sensation and dry-eye signs and symptoms after myopic laser in situ keratomileusis (LASIK) surgery with a femtosecond laser are affected by varying hinge position, hinge angle, or flap thickness.SETTING: University-based academic practice, Ann Arbor, Michigan, USA.METHODS: This prospective randomized contralateral-eye study evaluated eyes after bilateral myopic LASIK with a femtosecond laser (IntraLase). Superior and temporal hinge positions, 45-degree and 90-degree hinge angles, and 100 mu m and 130 mu m corneal flap thicknesses were compared. Postoperative follow-up at 1 week and 1, 3, 6, and 12 months included central Cochet-Bonnet esthesiometry, the Ocular Surface Disease Index questionnaire, a Schirmer test with anesthesia, tear breakup time (TBUT), corneal fluorescein staining, and conjunctival lissamine green staining.RESULTS: The study evaluated 190 consecutive eyes (95 patients). Corneal sensation was reduced at all postoperative visits, with improvement over 12 months (P