Pathogenesis of idiopathic osteonecrosis: the ubiquitous crescent sign.
Pathogenesis of idiopathic osteonecrosis: the ubiquitous crescent sign.
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特发性骨坏死的发病机制：普遍存在的新月征。
DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
Glimcher Mj
中科院分区：
文献类型：
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作者：
Kenzora Je;Glimcher Mj
一个大的软骨下骨坏死病变的修复遵循一个精确的生物学事件序列。随着软骨下骨折的发展，骨坏死的修复在放射学上表现为新月征，具有临床意义。一旦发生软骨下骨折，塌陷和随后的退行性关节炎通常是不可避免的。修复过程，影像学表现和临床特征（疼痛和功能丧失）是相同的，无论疾病的部位。
The repair of a large subchondral osteonecrotic lesion follows a precise sequence of biologic events. The repair of osteonecrosis becomes clinically significant with the development of a subchondral fracture manifested radiographically as the crescent sign. Once the subchondral fracture occurs, collapse and subsequent degenerative arthritis are generally inevitable. The repair process, radiologic appearance, and clinical features (pain and loss of function) are identical regardless of the site of the disease.